ÄKTA readyflux™ XL
Single-use filtration at multiple scales
Receive your quote directly from the manufacturer.
ÄKTA readyflux™ XL is an automated single-use filtration system designed for production of preclinical material and manufacturing of GMP-compliant material. The system is intended for cross-flow filtration (also called tangential flow filtration) in BioProcess™ applications in both upstream and downstream workflows.
To meet the capacity demands from single-use upstream processes (2000 L high-titer feeds), the system covers a wide feed pump flow rate from 5 to 60 L/min, using a standard flow kit with a recirculation loop of up to 1 inch inner diameter tubing.
The single-use flow path minimizes the need for cleaning and cleaning validation, allowing you to make a quick changeover between production runs, while eliminating the risk of carryover. The flow kit is easy to install, and the installation guide and test ensure correct functionality prior to a run. You also have the option for a fully closed operation using aseptic connectors.
ÄKTA readyflux™ XL system lets you take single-use filtration to manufacturing scale:
- Broad flow-rate range with a low hold-up volume and multiple filtration-control features provide versatility.
- Extensive documentation and single-use flow path make the system well-suited for use in multiproduct GMP facilities.
- Easily connect several mixers to increase capacity.
Extractables Studies on Single-Use Components in ADC Manufacturing
In this exclusive webinar, join Dr. Alfred Haglind, senior scientist and Mark Ayles, senior marketing manager, Cytiva, as they explain why antibody-drug conjugate (ADC) manufacturing is well suited to single-use technology due to small batch sizes and minimal operator exposure to toxins. Plus, explore why adding new components with more diverse materials into your processes means you will have to gather more extractables data.
The speakers will also share invaluable insights from Cytiva's recent study of extractables from single-use components used in ADC manufacturing. The study evaluated the compatibility of wetted materials and subcomponents with toxic solvents used in the process, the ReadyToProcess column housing, and the ÄKTA ready and ÄKTA readyflux™ flow kits, providing essential findings for optimizing ADC manufacturing processes.
Key learning objectives
- Discover the latest datafindings related to extractables and leachables (E&L) compatibility for multiple single-use components used in the conjugation of ADCs
- Understand E&L risks and ways to further mitigate the risks to improve regulatory compliance
Who should attend?
- MSAT, Quality, Process Development
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
