ÄKTA readyflux™ tangential flow filtration systems
ÄKTA readyflux™ is an automated single-use filtration system for pilot- and small-scale manufacturing. It's intended for tangential flow filtration applications in both upstream and downstream workflows.
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- Easy method preparation and flexible automation methods require no programming expertise and free up time for other activities.
- Three flow kit sizes with quick installation enable easy conversion of the system to meet different process requirements.
- Innovative and compact design with low minimum recirculation volume for high concentration factors and product recovery.
- Works with filter cassettes and hollow fiber filter cartridges for flexible microfiltration and ultrafiltration operations.
- Operates as a closed system when used with ReadyMate™ Flow Kit and ReadyToProcess™ hollow fiber cartridges.
Extractables in single-use systems used in ADC manufacturing
Antibody-drug conjugates (ADCs) are biotherapeutic molecules consisting of a cytotoxin coupled to a monoclonal antibody (mAb) by a linker. Single-use (SU) systems are well suited to ADC manufacturing for several reasons, such as minimizing operator exposure to toxins. Cytiva supports the adoption of SU technologies in ADC production by extractables studies, with conditions relevant to current ADC manufacturing processes. Discover how three SU products: ReadyToProcess™ 1 L column housing, disposable ÄKTA ready™ low flow kit for chromatographic systems, and ÄKTA readyflux™ flow kit for tangential flow filtration, demonstrate low levels of extractables with organic solvents DMSO and DMA.
Extractables Studies on Single-Use Components in ADC Manufacturing
In this exclusive webinar, join Dr. Alfred Haglind, senior scientist and Mark Ayles, senior marketing manager, Cytiva, as they explain why antibody-drug conjugate (ADC) manufacturing is well suited to single-use technology due to small batch sizes and minimal operator exposure to toxins. Plus, explore why adding new components with more diverse materials into your processes means you will have to gather more extractables data.
The speakers will also share invaluable insights from Cytiva's recent study of extractables from single-use components used in ADC manufacturing. The study evaluated the compatibility of wetted materials and subcomponents with toxic solvents used in the process, the ReadyToProcess column housing, and the ÄKTA ready and ÄKTA readyflux™ flow kits, providing essential findings for optimizing ADC manufacturing processes.
Key learning objectives
- Discover the latest datafindings related to extractables and leachables (E&L) compatibility for multiple single-use components used in the conjugation of ADCs
- Understand E&L risks and ways to further mitigate the risks to improve regulatory compliance
Who should attend?
- MSAT, Quality, Process Development
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
Cytiva launches new ÄKTA readyflux system for smaller scale manufacturing
Designed to support drug developers in bringing their therapeutics to market faster, more efficiently, and with greater reliability
Insights into the world of single-use technology
A panel of experienced specialists explore the significance of single-use technology (SUT) in biopharmaceutical manufacturing and biotechnology
