Waters Updates Alliance HPLC Designs without Impacting Established Validated Methods

25 Feb 2013
Sarah Thomas
Associate Editor

Waters Corporation today reinforced its commitment to high performance liquid chromatography (HPLC) users through new design improvements to the Waters® Alliance® HPLC System. Per customer demand, the updated system will maintain key Alliance performance specifications and control algorithms to ensure that analysts can seamlessly replicate their existing methods.

“The Alliance HPLC System has been the benchmark for HPLC in the laboratory for nearly two decades. Because of its dependability, high quality and flexible operation, tens of thousands of these systems are used every day to run methods varying from USP monographs to polymer analyses,” said Ian King, Vice President of Separation Science for the Waters Division. “Since its introduction, the Alliance HPLC System has been continually enhanced accommodating an enormous range of separation challenges. Waters will continue its commitment to upgrading the Alliance HPLC System with the assurance that any changes will not affect established, validated HPLC methods.”

Beyond updated electronics and user interface, the Alliance HPLC system is ideally suited to help scientists enhance their HPLC methodologies through use of Waters eXtended Performance [XP], 2.5 μm columns. These columns belong to Waters’ platform of scalable particle size chemistries, which includes our patented surface charged column chemistries, which due to their wide selectivity range can seamlessly reproduce existing HPLC methods and simultaneously provide a pathway to UPLC® compatibility for the future. Waters’ HPLC to UPLC method transferability strategy differentiates us from other competitors.
Additionally, the ability for Alliance HPLC to seamlessly integrate with customers’ existing Empower® software network for instrument control and data processing significantly expands the impact of the system. Empower 3 Software, Waters’ flagship chromatography data software, makes it easier than ever to run samples and produce meaningful results without extensive training, re-engineering workflow, or adding new software to support instruments or advanced chromatographic techniques.

Analytical laboratories depend on the Alliance HPLC System to meet the rigorous requirements ranging from routine analyses to the performance standards of new product research and development. Whether a lab specializes in pharmaceutical, chemical, food safety, environmental, or quality control analyses, the Alliance HPLC system offers:

•Integrated solvent and sample management to ensure consistent system-to-system performance and high reproducibility;
•Alliance HPLC features with Automated Solvent Compressibility, users do not have to select from calibration or look-up tables, and risk accidental errors in selection.
•Full integration with either Empower or MassLynx® Software for instrument control and data processing;
•A large, intuitive LCD-based user interface for rapid system set-up and daily start-ups;
•Easy, tool-free maintenance resulting in maximized uptime;
•Waters complete line of detection technologies – from routine UV/Vis detectors to single, tandem and triple quadrupole mass spectrometers - extend application capabilities
•Supported by Waters 50 years of HPLC expertise and global reach in every country where Waters is represented.

Waters Alliance™ HPLC System

Waters

An integrated HPLC system that works as hard as you do, available with push-button mass detection for the chromatographer. The Alliance™ HPLC System is the flexible and reliable workhorse that meets your fundamental HPLC separation requirements. The system has been continually expanded and perfected to accommodate an enormous range of real-world analytical challenges, culminating in today’s new industrial design which signifies Waters’ commitment to HPLC and our HPLC line. Today, users can extend the Alliance HPLC System’s performance with XP 2.5 µm Columns. XP Columns are compatible with both HPLC and UPLC technology and are designed to not only improve our HPLC productivity, but also facilitate a transfer to UPLC Technology platforms as well. Directly scalable between UPLC and HPLC particle sizes, these new 2.5 um XP Columns bridge the gap between HPLC and UPLC performance. Whether your lab analyzes samples in the pharmaceutical, chemical, food safety, environmental, or quality control arenas, the Alliance HPLC system offers you a field-proven solution. Integrated solvent and sample management to ensure consistent system-to-system performance and high reproducibility. Waters Alliance™ HPLC System Features: Full integration with either Empower® or MassLynx® Software for instrument control and data processing A large, intuitive LCD-based user interface allows rapid system set-up through SystemPREP routines that streamline daily start-ups Easy, tool-free maintenance resulting in maximized uptime Waters complete line of detection technologies – from routine UV/Vis detectors, to the ACQUITY QDa Detector to single, tandem and triple quadrupole mass spectrometers - extend your application capabilities

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Empower™ Chromatography Data System

Waters

The Empower Chromatography Data System is Waters’ compliance-ready chromatography data software (CDS) for advanced data acquisition, processing, and reporting that simplifies the management of chromatography test results.

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Waters Updates Alliance HPLC Designs without Impacting Established Validated Methods