Product News: Waters introduces the new DESI source for the Xevo TQ Absolute system

Waters Corporation has launched the industry's first targeted imaging mass spectrometer based on its Xevo^™ TQ Absolute tandem quadrupole mass spectrometer, the most sensitive and compact mass spectrometer in its class. The new instrument combines the Waters^™ DESI XS source with the Xevo TQ Absolute system and is five times more sensitive and five times faster than discovery-based imaging systems at precisely determining whether a particular small molecule drug product – and how much of it - reaches its intended target, such as a brain, liver, or lung, in a test subject.

Applications for direct-from-sample DESI/tandem quadrupole mass spectrometry include:

• Elucidating drug distribution in tissue sections

• Monitoring relevant biochemical pathways in toxicological studies

• Classifying tissue and determining tumor margins

At this year's ASMS conference, Waters is also showcasing its PFAS analytical workflow based on the ultra-sensitive Xevo TQ Absolute mass spectrometer, chemistries, and software. The end-to-end UPLC-MS workflow allows laboratories worldwide to upgrade their capability and keep current with the latest regulatory requirements for measuring parts-per-quadrillion levels of PFAS in air, water, soil, and food.

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