New System for Fast and Consistent Results Makes UHPLC Widely Accessible

Thermo Scientific Vanquish Flex Binary UHPLC system boosts high-speed applications and provides exceptional LC and LC-MS performance

20 Jun 2016
Weylan Kiam-Laine
Microbiologist

Researchers looking for fast and consistent results can now benefit from the new ultra high-performance liquid chromatography (UHPLC) system from Thermo Fisher Scientific to boost their LC and LC-MS performance.

As the latest addition to the Thermo Scientific Vanquish UHPLC platform, the new Thermo Scientific Vanquish Flex Binary UHPLC system adds a binary solvent delivery option in the 1000 bar (15,000 psi) performance range. The system is built for high-speed, fast gradient applications and the Vanquish platform’s inherent outstanding retention time reproducibility. The Vanquish Flex Binary UHPLC system is the solution for laboratories performing qualitative and quantitative LC or LC-MS analysis that need to increase sample throughput. Ease-of-use and innovative technologies that are robust by design are making UHPLC widely accessible and enable easy and effective method transfer from established systems and applications.

“As the newest addition to our Vanquish platform, we developed this system with speed, sensitivity and quality results in mind—providing the level of operational efficiency required by today’s researchers,” said Fabrizio Moltoni, vice president and general manager, HPLC at Thermo Fisher. “The Vanquish Flex Binary system showcases these attributes and provides exceptional LC and LC-MS performance together with our products for sample preparation, reagents, columns, mass spectrometry and data processing.”

The Vanquish Flex Binary System features a binary high-pressure gradient pump with 2 x 3 solvent channels and low gradient delay volume capable of delivering high flow rates of up to 8 mL/min. The entire system provides biocompatible flow path, SmartInject using intelligent sample pre-compression, selectable thermostatting modes and a unique range of detection capabilities.

The Vanquish Flex Binary system will be exhibited at the 44th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC) in the Thermo Fisher Booth #601 from June 19-24 at the Marriott Marquis in San Francisco.

Thermo Scientific™ Vanquish™ Flex Quaternary UHPLC System

Thermo Fisher Scientific

The Thermo Scientific™ Vanquish™ Flex Binary UHPLC system is biocompatible with a state-of-the-art binary high-pressure pump and state-of-the-art binary solvent blending. This ultra high performance liquid chromatography system shares all Vanquish values, such as a design focused on uptime, robustness and reliability. Multiple detection options as well as Thermo Scientific™ Viper™ fingertight connections throughout the system will give you the performance you need with the ease of use you want. Our SmartFlow™ pumping technology with automatic compensation for changing eluent compressibility ensures excellent flow and gradient precision, independent of eluent composition and backpressures. This gives you unrivaled retention time precision and highest data confidence, even for ternary and quaternary gradients, and for more freedom in method development and application switching. Detection capabilities include high sensitivity and linearity Diode Array Detection with LightPipe technology, selective and sensitive Fluorescence Detection and near-universal detection capabilities with the Vanquish Charged Aerosol Detector. Key Features: Integrated modularity design concept to offer uncompromising UHPLC State-of-the-art quaternary solvent blending 1000 bar of pump pressure and flow rates up to 8 mL/min Industry-leading flow and gradient precision Multiple detection options including DAD, FLD and CAD Relevant Applications: Separations of Intact mAbs Analysis of labeled glycans Ternary gradient impurity profiling Efficient, reliable peptide mapping

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New System for Fast and Consistent Results Makes UHPLC Widely Accessible