Product News: BINDER CO2 incubators for the best cell growth

The CB and CBF series incubators provide optimum, reproducible growth conditions for cell cultures with minimum risk of contamination

19 Mar 2024

 

Cell cultivation is a demanding and highly sensitive process which requires optimum and reproducible growth conditions. As CO2 incubators play a crucial role in this process, BINDER has developed units that meet the highest standards.

Preventing contamination

BINDER CO2 incubators provide optimum, reproducible growth conditions for cell cultures with minimum risk of contamination. The 180°C hot air sterilization reliably kills bacteria and spores, effectively performing a biological reset when each individual trial series is introduced.

Interior conditions have to remain clean while cell cultivation is taking place. The deep-drawn, seamless, stainless steel inner chamber and the rounded corners in the interior ensure that the BINDER CO2 incubators are easy to clean. The rounded flanges that serve as a shelf support system mean that there are no corners where hidden contamination could accumulate.

Fixtures such as fans, air baffle plates, and filters have been omitted from the incubators deliberately. The fanless interior means that germs cannot spread through the air, thus preventing contamination of the cell cultures.

Another important part of the anti-contamination concept is the humidity limitation, which prevents contamination occurring even if humidity levels are high. The cold spot on the base of the chamber represents the coolest point in the interior and is located in the water pan. Excessive humidity can condense here without settling elsewhere in the inner chamber. This keeps the interior walls dry and prevents mold from forming.

Stable pH values

In the BINDER CO2 incubators, homogeneous gas distribution and quick mixing by the gas mixing head with Venturi effect ensure stable pH values. Responsive measurement without drift and the CO2 measurement system with its infrared sensor technology also play a part in keeping the pH values constant.

The models in the CB and CBF series are equipped with a CO2 sensor that can be sterilized with hot air and can therefore remain in the unit during hot air sterilization.

A key feature of the BINDER CO2 incubators is the patented CO2 fail-safe system that protects the pH value of the cell cultures. In the event of a sensor failure, underexposure or overexposure to CO2 is prevented and the CO2 concentration is maintained in a range that enables the cell cultures to survive.

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