Industry News: ENPICOM partners with Erasmus University Medical Center in an effort to discover nanobodies against cancer

Erasmus University Medical Center uses ENPICOM’s IGX Platform and services to advance their research on identifying cancer nanobodies

21 Feb 2024

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ENPICOM's immune repertoire data analysis software solution

ENPICOM, an innovative bioinformatics software solutions provider, has announced a collaboration with Erasmus Medical Center, Rotterdam, a distinguished leader in cancer research. The aim of this partnership is to identify and develop nanobodies against cancer by utilizing ENPICOM’s immune repertoire data analysis services and software solutions.

Compared to traditional antibodies, nanobodies are much smaller, enhancing tissue penetration and tumor infiltration. Moreover, nanobodies tend to have longer CDR3 regions, enabling them to better recognize hidden epitopes. Their simple single-chain structure also grants nanobodies greater stability and ease of production and engineering.

ENPICOM’s IGX Platform is specifically designed to analyze antibody sequencing data and discover a diverse set of developable candidates. The software seamlessly integrates sequence and experimental assay data, allowing for efficient cluster, phylogenetic, and display enrichment analyses in a secure and scalable environment. Moreover, to ensure the best antibody candidates are selected for follow-up studies the platform enables high-throughput structural modeling of antibodies to accurately identify and annotate exposed liabilities. This makes it a powerful solution to streamline any antibody discovery workflow and easily identify the best antibody candidates for further development.

In addition to the IGX Platform, ENPICOM offers full-service immune repertoire sequencing and analysis in collaboration with Cerba Research. Furthermore, ENPICOM offers on-demand repertoire analysis and custom development to support non-standard R&D – a solid combination of immunology, bioinformatics and software engineering to take on anything touching adaptive immune repertoires.

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