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BIORON and GENAPSYS start cooperation in Germany to offer new DNA-sequencing technology

BIORON GmbH

The new cooperation aims to use BIORON's molecular biological tools and GENAPYS unique sequencing technology

25 Jan 2021
Diane Li
Assistant Editor

Industry news

By February 2021, BIORON will represent GENAPSYS in Germany and will offer a new sequencing system and technology for a broad scale of customers in academia and industry. The new cooperation gives ideal synergy effects between BIORONs molecular biological tools and the unique sequencing technology of GENAPSYS.

The high demand in Germany for biological surveillance and the increased demand for genetic data information offers sequencing labs new opportunities. The GENAPSYS system generates DNA sequence information based on a new method and technology. GENAPSYS developed a novel electrical-based platform capable of accurately detecting single base incorporations. The semiconductor chip-based detection modality allows the system to be compact, scalable, and affordable. In combination with the smart sample preparation tools of BIORON for the isolation, amplification, fragmentation, and labeling of the targeted probes, we can now offer an end-to-end solution to individual research labs for many sequencing applications.

With this precise and cost-effective sequencing technology available, more research labs and life science companies can be enabled for the SARS-CoV-2 pandemic control and monitoring for a better understanding of the pandemic and the virus itself. The UK-NHS labs analyze 20-times more clinical Corona samples in comparison to the German virus reference labs due to the missing appropriate systems and resources. GENAPSYS offers a complete process for the necessary routine monitoring of the virus variants. More information at https://www.genapsys.com/our-applications/

Several research labs in Europe have requested and installed the GENAPSYS technology in 2020 and the chip-based DNA sequencing process shows several advantages. The integration of standardized sample preparation, sequencing and data interpretation offers a great complement to existing sequencing methods and establishes a new standard. The turnaround time and operating cost are very competitive compared to other commercial solutions. The sample handling is compatible with the standard lab procedures and the systems require less space and maintenance compared to other NGS systems.

Dr. Armin Winands / GENAPSYS Europe and Simon Koerpert / BIORON GmbH are responsible for the cooperation and distribution of both Life Science portfolios and the synergy effect will offer a professional service and support for all existing and new customers. Now both companies bring in the right tools with the best timing.

The BIORON-GENAPSYS cooperation is very important and the chip technology of GENAPSYS is similarly unique to the SD-Polymerase of BIORON. It is specially designed enzyme for DNA amplification. This key enzyme is already a standard enzyme for Single Cell Whole Genome Amplification, One Step Whole Genome Amplification, DNA Fragmentation, DNA-Library generation and Liquid Biopsy with the Cell-free Extraction kit.

This means, besides the current application for the virus variant monitoring, both product portfolios can be used for Cancer Research, PID-Diagnostics, HLA-Analytics, and individual precision medicine of the future.

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DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA / RNA QuantificationDetection and quantification of nucleic acids is important in molecular biology, cloning, expression, forensics and clinical diagnostics. Nucleic acids can be detected by labeling with colorimetric, fluorescent or radio labels and using in situ hybridization kits to identify specific sequences. Multiple nucleic acids can be detected and quantified at once using RNA / DNA detection beads or RNA / DNA microarrays. Find the best DNA / RNA Quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Molecular BiologyMolecular biology is the branch of biology that focuses on the molecular mechanisms that underlie cellular functions. It involves studying DNA, RNA, and proteins to understand gene expression, replication, and regulation. Molecular biology is fundamental to biotechnology, medicine, and genetic research. Explore molecular biology products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.DNA QuantificationDNA quantification is the process of measuring the amount of DNA in a sample. It is vital in genomics, molecular biology, and biotechnology, helping to ensure accurate experiments and data analysis. Explore DNA quantification tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.NGSMutationMutations are changes in the DNA sequence that can lead to diseases, including cancer and genetic disorders. Analyzing mutations is crucial in diagnostics, drug development, and personalized medicine. Explore mutation detection tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.SequencingSequencing refers to determining the order of nucleotides in a DNA or RNA molecule. This process is essential in genomics, diagnostics, and evolutionary biology. Techniques like next-generation sequencing (NGS) and Sanger sequencing provide high-throughput and precise data for analyzing genomes and transcriptomes. Browse our peer-reviewed product directory to find the best sequencing tools and reagents, compare products, check reviews, and get pricing directly from manufacturers.VirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.Genome SequencingGenome sequencing involves determining the complete DNA sequence of an organism's genome. It provides crucial information about genetic variations, mutations, and diseases. Advances in sequencing technologies, such as next-generation sequencing (NGS), have accelerated research in genomics, diagnostics, and personalized medicine. Explore genome sequencing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Genetic VariationCoronavirusCoronaviruses are a large family of viruses that can cause illnesses ranging from the common cold to more severe diseases like COVID-19. 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