ELRIG ADVANCES IN CELL-BASED SCREENING IN DRUG DISCOVERY 2024

The fifth ELRIG meeting on Advances in Cell Based Profiling in Drug Discovery will be held on May 15-16 2024 at the AstraZeneca R&D site in Gothenburg. The interactive 2-day event will host leading scientists from academia, industry and the vendor community to discuss current and future formats for cell based assays.

Cell based assays are utilized at all stages of drug discovery to explore disease mechanisms and to identify novel molecular therapeutics. To achieve this the field is continuously looking for improvements in cell reagents, assay formats, and readouts to ensure disease-relevant contexts, aiming at improving translation to human physiology. Implementation of cell assays with improved translatability is much needed for improving success rates in drug discovery, but we are struggling with restrictions in cell availability and assay costs, considerations that are holding back their broader implementation. This meeting will explore these challenges and look into how cell profiling efforts must be adapted to emerging drug modalities, in this case with a special focus on therapeutic oligonucleotides and other modalities that affect protein levels rather than their activities.