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Virus-based tools for cell engineering

AMSBIO

New range of Vesicular Stomatitis Virus vectors offer a robust model of viral infection for cell engineering applications

31 Oct 2022
Blake Forman
Content Creator

Product news

AMSBIO has added a new range of Vesicular Stomatitis Virus (VSV) to its suite of virus-based tools for cell engineering and the study of viral infection.

Vesicular Stomatitis Virus is an enveloped, negative-stranded RNA virus with a simple structure. Its ability to infect a wide range of mammalian cell types has made it a valuable tool to study virus entry, replication, and assembly. A key advantage of the AMSBIO VSV model is that it undergoes only one round of replication. Consequently, it is safe to use and requires only a biosafety level 2 facility.

VSV vectors offer a robust model of viral infection that can be efficiently pseudo-typed with envelope glycoproteins derived from heterologous viruses, making them highly suitable for studying the entry mechanisms of such high-risk viruses.

Drawing upon proprietary technologies and reagents, recombinant VSV vectors from AMSBIO benefit from top-quality production protocols that deliver products unmatched in terms in terms of titer, purity, viability, and consistency.

Recombinant VSV vectors from AMSBIO are the viral product of choice for a growing variety of applications including studying mechanisms of viral entry into host cells, identification of cellular receptors used by viruses for cell entry, screening of viral entry inhibitors, and vaccine development research.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Cell AnalysisThe analysis of cells allows researchers to understand the factors which contribute to cell health and function. These influencing processes can then be predicted and altered, leading to the development of medication and disease treatments.VirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.Vaccine DevelopmentVaccine development focuses on creating immunizations to protect against infectious diseases. The process involves identifying antigens, developing and testing vaccine efficacy, and ensuring safety through preclinical testing and multiple clinical trial phases. Scientists use various approaches, including weakened or inactivated viruses, protein subunits, or mRNA. Advanced platforms and rapid diagnostic tools aid in vaccine research and testing. Explore vaccine development solutions in our peer-reviewed product directory; compare products, read reviews, and get pricing directly from manufacturers.

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