Thermo features the newest LXQ applications that highlight rapid and reliable structural identification and quantification

14 Nov 2006

Thermo Scientific, the world leader in analytical instrumentation, features the newest applications highlighting the LXQ High Throughput Linear Ion Trap. High throughput drug discovery, robust analysis of oral fluid for multiple illicit drugs, and the analysis of complex proteomic samples are highlighted in this application feature.

The LXQ delivers linear ion trap performance for high throughput solutions in today’s fast-paced analytical laboratory. The fast cycle time and high sensitivity of the LXQ enable rapid and reliable structural identification and quantitation for a wide array of applications including:

  • Impurity and stability studies
  • Metabolism / metabolomics
  • Drug screening
  • Protein analysis

Make decisions faster and with more confidence, increase your lab’s productivity without sacrificing quality, and experience true performance with high MSn spectral quality, sensitivity, and fast cycle times.

New Featured Applications

  • A High Throughput Approach for Metabolite Profiling and Characterization
  • Analysis of Multiple Illicit Drugs, Methadone and their Metabolites in Oral Fluid
  • Analysis of a Complex Sample of Bacterial Whole Cell Lysate from Haemophilus ducreyi

Thermo Scientific LXQ Linear Ion Trap Mass Spectrometer

Thermo Fisher Scientific

The LXQ, designed for drug discovery, forensics, proteomics and a variety of industrial applications, offers fast cycle time with the increased sensitivity of a linear ion trap, at an attractive price. Technology You Can Trust From the leaders in linear ion trap technology High sensitivity for detection of multiple analytes in complex matrices Confident structural identification Fast cycle times for high-throughput analyses Patented linear ion trap design enables high-quality MSn characterization Routine protein and peptide analysis Maximize LC/MS information with rapid and reliable compound detection and structural identification A high-throughput strategy, including simultaneous identification and quantification of multiple drugs, is necessary to accelerate lead optimization. Such studies provide feedback to guide synthesis efforts, and to optimize pharmacokinetic and safety characteristics of drug candidates. The combination of fast cycle time and high spectral quality using the LXQ is key to quickly screening for drugs and their metabolites. Quantification and robustness for forensics The LXQ delivers high accuracy and precision for quantitative analysis, along with a linear dynamic range of four orders of magnitude. The high ion storage capacity of the LXQ linear ion trap provides reliable quantification in complex matrices with superior qualitative results. Increase productivity with reliable instrument operation The Ion Max™ source and the LXQ offer outstanding robustness for the most demanding analytical applications. As leading innovators of ion trap technology, Thermo ion traps are built from the best-integrated designs resulting in long-term operation and consistent spectra generation. Rapid screening for proteomics The LXQ offers routine protein and peptide identification. The LXQ delivers high sensitivity MS/MS spectra for resolving coeluting peptides often seen in protein digests. The high spectral quality of the LXQ results in high correlation scores for confident sequence identification.

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