Streamlining process scale-up with the new Eppendorf BioFlo 720 bioprocess controller

14 Jan 2021
Edward Carter
Publishing / Media

Streamlining the transfer of an upstream bioprocess from research to production scale is critical for reducing biologics development costs and time to market. Eppendorf, one of the leading life science companies, has introduced the BioFlo 720, a bioprocess control station for applications at pilot/production scale using single-use bioreactors. With it, Eppendorf now offers one of the most scalable and comprehensive single-use portfolios on the market, for seamless process scale-up from R&D labs to pilot and manufacturing facilities.

“The BioFlo 720 is compatible with Thermo Fisher Scientific™ HyPerforma™ 5:1 single-use bioreactors. In combination with our BioBLU® Single-Use Vessels for small and bench scale bioprocesses we offer pharmaceutical and biotech companies the benefit of an integrated scalable portfolio, including manufacturing solutions for regulated environments," says Dr. Karl Rix, Vice President of the Bioprocess Business Unit at Eppendorf.

Innovative software features help saving time, increase efficiency, and reproducibility by automating repetitive process steps:

  • Auto Inflate automatically controls the inflation process for flexible single-use bioreactors
  • Auto Calibrate automatically calibrates all attached DO sensors at once
  • Scale Up Assist calculates scaling-relevant parameters based on constant tip speed or power input per volume

For added flexibility, configurable gas flow control, sensor connections, pump options, and software settings enable the system to meet a variety of process needs.
With a narrow footprint of only 81 x 87 cm (32” x 34”) the BioFlo 720 minimizes space utilization. Designed as a mobile controller it can be quickly deployed into any bioprocess project in research or regulated environments.

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Eppendorf New Brunswick™ BioFlo® 610

Eppendorf

The BioFlo 610 is a compact, mobile, pilot-plant fermentor for process development and small-scale production. A modular design and wide variety of standard and optional components provide the flexibility to customize the system to meet your process requirements.   Eppendorf New Brunswick™ BioFlo® 610 Working volumes: 16.0 L to 50.0 L 32.0 L to 100.0 L Applications: Pilot scale fermentation of aerobic and anaerobic bacteria, yeasts, and fungi; Special applications such as vaccine or biofuel/biopolymer production; Suitable for batch and fed-batch processes

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