Standalone flow chemistry module for exothermic reactions

The ColdChip aims to provide a flexible and efficient platform to run exothermic reactions

9 Sept 2022
Dora Wells
Clinical Content Editor

Uniqsis has launched ColdChip™ - a new versatile mixer/reactor module enabling researchers to experiment with different chemistries particularly exothermic reactions that need to be safely run in a cooled environment with highly efficient mixing.

Compact in design and requiring no input power, the ColdChip™ is optimized for use with the Uniqsis FlowSyn and FlowLab range of flow reactors as well as standalone pumps. Designed to work with most recirculating chiller/heater units - the ColdChip™ can deliver a stable operating temperature (-70ºC to +180 ºC) and pressure (up to 40 Barr) environment in glass static mixer chips ranging from lower volumes (270µl, 1ml, or 2 ml) to single residence time chips (10, 15 and 20 ml).

To enhance operator safety and ease-of-use the ColdChip™ includes a PTFE safety cover, a glass window to view the glass static mixer, and an open area located at the back for easy access to the glass static mixer inlet/outlet turret connectors.

Want the latest science news straight to your inbox? Become a SelectScience member for free today>>

FlowSyn Continuous Flow Reactor

Uniqsis Ltd

FlowSyn - Making Flow Chemistry Simple FlowSyn is a fully integrated continuous flow reactor with everything you need to start doing flow chemistry including reaction optimization, synthesis and scale up. To provide maximum flexibility, a wide range of mixer and reactor options are available as well as additional modules for performing multiple experiments, or sub-ambient chemistry. • Ability to perform continuous flow chemistry under microwave-like conditions (up to 260oC). • Perform sub-ambient continuous flow chemistry using the 'Cold Coil'. • Run up to 10 automated sequential experiments with the 'Automated Experiment Package'.A pair of high pressure pumps are used to deliver reagent solutions from either stock bottles or sample injection loops through a 'T'-mixer into the electrically heated flow reactors. Reactions can be heated to 260?C and 150?C in the coil and column reactor modules respectively. Back pressure regulators of up to 1000 psi are used to pressurise the system and thus perform superheating of solvents, allowing the chemist to access'microwave like' conditions with no limitation on scale. FlowSyn is very easy to use with a high resolution user interface. The user is guided through the process for setting up a flow chemistry reaction by inputting parameters for reagent volumes, temperatures and reaction times. The user can choose to collect all of the reaction plug, or only the 'steady state' part. FlowSyn will then equilibrate and run the reaction, and finally flush the system through with solvent. Throughout FlowSyn will monitor the pressure of the system, and shut down if a problem occurs allowing FlowSyn to be safely run unattended.

(0)

Links

Tags

Standalone flow chemistry module for exothermic reactions