Smarter cleanup for lentiviral manufacturing

29 Jul 2025

Discover how ArcticZymes Technologies' M-SAN HQ nuclease enhances lentiviral vector manufacturing by efficiently removing host cell DNA, including chromatin, under physiological salt conditions. This simple yet powerful solution helps improve vector yield, streamline downstream processing, and reduce regulatory risks.

Bioprocessing Salt Active Nucleases - Physiological Conditions

ArcticZymes

Nonspecific endonuclease is highly active at physiological conditions (125–200 mM) for DNA removal during protein production, vaccine manufacturing, and viral vector preparation. M-SAN High Quality can be used directly in cell media, which improves efficiency and yield. Designed to replace Benzonase without workflow changes. M-SAN HQ excels in ensuring higher purity and efficiency. High purity (≥ 99%). Compatible with ELISA kit.

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