Scaling Up Screening in 96- & 384-Well Microplates

8 Dec 2015
Lois Manton-O'Byrne, PhD
Executive Editor

INTEGRA reports on how researchers at the Health Innovation Research Institute at RMIT University are using VIAFLO II electronic pipettes in conjunction with a VIAFLO ASSIST to scale-up their screening of venoms and small compounds.

The Health Innovations Research Institute (HIRi) is an RMIT University initiative that seeks to address key health issues facing Australia in the 21st century, with research programs that examine how the human body functions at a molecular and cellular level. This research is targeted to provide innovative therapeutic strategies to improve the health and wellbeing of people in Australia and around the world.

Bill Darby, a Researcher at HIRi, commented "We approached INTEGRA’s Australian distributor (BioTools Pty Ltd.) for a solution to scale-up our screening of venoms and small compounds in both 96- and 384-well plates. Following a demonstration, we found that the VIAFLO ASSIST pipetting assistant met our required criteria of a cost effective and easy to use pipetting solution, which lead us to purchase the ASSIST and 3 VIAFLO II multichannel pipettes”.

Mr Darby added “Since its introduction, the system has been running perfectly and we have been able to achieve the scaling-up we required. The ASSIST has delivered more accurate and precise pipetting results that have improved our assay results. Another significant benefit is that the ASSIST is very compact and easily fits in our lab hood. We have also found that the versatility of the VIAFLO II pipettes has proven especially useful for handling complicated layouts in 384-well plates”.

VIAFLO Electronic Pipettes

INTEGRA Biosciences

Electronic pipettes with touch wheel user interface.   VIAFLO pipettes accommodate any pipetting task at hand: from single transfers to complex protocols. An intuitive touch wheel interface and color display allows for the quickest volume changes and user friendly menu navigation. The ergonomic design enables effortless pipetting. The unique tip fitting of the VIAFLO pipette assures that GripTip pipette tips will never loosen, leak or fall off. VIAFLO Electronic Pipettes Features:   GripTip Pipette Tips - By designing our GripTips™ in tandem with VIAFLO pipettes, we have created a unique, integrated system that offers the securest pipette and pipette tip connection. High lateral resistance. This prevents tips from falling off when touching off a multichannel pipette within a 96 or 384 well plate. Low required tip attachment forces. Low required tip ejection forces. All tips seal at the same height ensuring a perfect touch off and increased precision when dispensing. Intuitive User Interface - A full color screen and a proven touch wheel interface offer quick and comprehensible menu navigation. Simply by moving a finger over the touch wheel, menus and settings can be accessed. All menus are spelled out on the clear to read screen making memorizing of abbreviations unnecessary. Convenient Pipette and Program Management - VIAFLO pipettes can be connected to a computer via USB port. With the free to use pipette management software VIALINK, custom programs can be created on the computer and then be transferred onto VIAFLO pipettes. For laboratories with many users or power users with many pipetting protocols, all custom programs can be stored and backed up in a library on the computer. Applications: Repeat Dispense Manual Pipetting Sample Dilution Reverse Pipetting Variable Dispense

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Scaling Up Screening in 96- & 384-Well Microplates