Phenomenex Introduces Clarity™ BioSolutions

Phenomenex Inc., Torrance, USA introduces their new product portfolio for the purification of synthetic oligonucleotides, Clarity™ BioSolutions.

Clarity BioSolutions is a portfolio of products, including desalting tubes, HPLC columns, and NEW, state-of-the-art cartridges, for the purification of synthetic oligonucleotides. A variety of purification options are provided to support different purification strategies based on purity and yield requirements, throughput goals, diverse oligo chemistries, and lab resources.

NEW Clarity Triophilic™ Purification Cartridges have a specifically engineered sorbent that purifies a desired full-length oligonucleotide sequence from failure sequences and other impurities. The cartridges deliver 90-95% purity and yields using a universal, simple protocol for all oligonucleotide chemistries including DNA, RNA, siRNA, phosphorothioates, dye-labeled, etc. The innovative multi-plex format results in the purification of 96 samples in less than 30 minutes and is amenable to automation.

Clarity Oligo-RP is a line of reversed phase HPLC columns designed for the purification of synthetic DNA and RNA. The column media is based on TWIN™ technology and gives improved selectivity and efficiency. This results in 95% typical purity, loading capacity from 50nmole to greater than 5µmole, and ability to easily separate n-1mer from target sequence.

Clarity desalting tubes typically provide 70% purities and 80% recoveries in a disposable format. This product is suitable for those who only require moderate purification of their oligonucleotide or simply want to remove salt from the synthesis sample.