Pall Introduces Next Generation AcroPrep Advance Filter Plates

26 Feb 2010
Sarah Sarah
Marketing / Sales

Pall Corporation introduces its next generation 96-well filter plate that delivers consistency and reproducibility in applications, such as neonatal screening and multiplexing. The Pall AcroPrepTM Advance filter plate employs new design features that provide uniform filtration rates, lowers hold-up volumes and ensures consistent sample/bead recovery from the wells.

Pall’s newest AcroPrep filter plates address the most stringent sample preparation requirements while lowering the expenses associated with sample loss and contamination. Redesigned membrane sealing technology maximizes sample recovery and ensures even filtration rates well to well. The optimized outlet tip design minimizes weeping during incubations as well as the formation of post-filtration hanging drops. The biologically inert housing of the plates facilitates low non-specific binding of target analytes, maximizing sample recovery. These new design features translate into superior performance over competitive plates. Examples of this include faster acquisition times for multiplexing applications, as well as more consistent enzymatic responses in neonatal screening assays.

“The AcroPrep Advance filter plates have been developed to address the needs of key diagnostic assays,” said Emily Berlin, Senior Marketing Manager at Pall Life Sciences. “These plates have been optimized to ensure superior performance where consistency and reproducibility are critical. Our new plate line offers advanced performance from well-to-well, plate-to-plate and lot-to-lot.”

Engineered to minimize sample hold-up, the new well design significantly improves filtration rates and sample recovery to ensure assay reproducibility. Plus, the new AcroPrep plates reduce weeping, which is a common problem during incubation periods or after multiple filter-wash-incubation steps. Pall’s new AcroPrep Advance filter plates meet SBS/ANSI guidelines for manual, semi-automated and automated processing. Additional plates in Pall’s product portfolio are used for general filtration, lysate clarification, nucleic acid and protein purification applications.

AcroPrep™ Advance Filter Plates for Protein Purification

Pall Life Sciences - Laboratory, Food, Beverage

AcroPrep™ Advance Filter Plates- Advancing sample preparation Features of the AcroPrep™ Advance Filter Plates:  •  Smooth well design – Provides consistency in filtration times, as well as efficient sample and bead recovery.   •  Optimized outlet tips – Minimizes sample leakage during incubation steps and reduces the presence of hanging drops following filtration.   •  New well geometry – Results in faster , more uniform filtration rates across the plate, thereby improving well-to-well, plate-to-plate, and lot-to-lot consistency.   •  100% visual inspection – Ensures each well has proper membrane placement and is free from debris.   •  Automation compatible – Manufactured in accordance with SBS guidelines, allowing plates to be run in manual, semi-automated, and automated processes. Applications of the AcroPrep™ Advance Filter Plates:  •  Lysate clearance   •  DNA purification   •  Protein purification   •  Multiplexing assays   •  Bead-based assays   •  Flow cytometry   •  Neonatal screening   •  Size exclusion   •   Concentration, purification, and desalting of proteins and nucleic acids   •  Aqueous filtration   •  Particulate removal   •  Solvent filtration

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Pall Introduces Next Generation AcroPrep Advance Filter Plates