Oxford Gene Technology Launches CytoSure Products for the Cytogenetics Research Community

5 Jul 2007

Product news

Oxford Gene Technology (OGT) announces the launch of two array CGH (aCGH) products designed exclusively for the cytogenetics research community. Branded under the family name CytoSure™, Syndrome Plus and Chromosome X exon specific arrays will debut at the European Cytogenetics Association conference in Istanbul, 7th-10th July, 2007.

CytoSure Syndrome Plus is a 105,000 feature array covering the whole genome, and includes probes designed to 85 constitutional syndromes - including Cri du Chat, di Georges and Prader-Willi – and other clinically relevant regions.

CytoSure ChrX array, a 44,000 feature array, has been developed in collaboration with Dr Philippos Patsalis, Chief Executive and Medical Director at the Cyprus Institute of Neurology and Genetics in Nicosia, Cyprus. This unique design provides comprehensive coverage of all relevant clinical areas across the X chromosome at high resolution.

CytoSure arrays will be supplied with complimentary visualisation software incorporating Copy Number Variation, gene and exon annotation to ease data interpretation and build confidence.

Dr Mike Evans, CEO of Oxford Gene Technology said: “We are very excited at OGT to be launching the CytoSure family – these are the only oligonucleotide arrays designed exclusively for the cytogenetics community and will enable cytogeneticists to achieve accurate, high resolution analysis of chromosome copy number and structural changes.”

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.OligonucleotidesOligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.
Oxford Gene Technology Launches CytoSure Products for the Cytogenetics Research Community