OGT Offers New Genomic DNA Labelling Kit for Cytogenetics Array

16 Feb 2009
Samantha Rosoman
Campaign Coordinator

Product news

Oxford Gene Technology (OGT), the pioneer of microarray-based technologies, has launched a Genomic DNA labelling kit offering a fast and simple protocol. The labelling kit, which is fully optimised for OGT’s CytoSure™ family of high resolution oligonucleotide arrays, adds to the Company’s comprehensive portfolio of products and services, which together provide a complete solution for cytogeneticists, from sample to result.

The Genomic DNA labelling kit contains Cy3 and Cy5 dyes for dual-colour hybridisations, and uses a unique buffer formulation to allow more efficient use of reagents without loss of signal intensity. The kit contains everything required for the protocol, including nucleotide mix, random primers, enzymes and even the clean-up columns and collection tubes. OGT also offers analysis software to allow easier interpretation of results with data exchange for comprehensive, state-of-the-art cytogenetic profiling, and comprehensive training for customers of its CytoSure arrays.

Barbara DuPont, Director of the Cytogenetics Laboratory at the Greenwood Genetic Center in South Carolina, USA, which provides diagnostic and clinical genetics services, said: “We have moved from the BAC platform to using OGT’s CytoSure arrays, and it was a very easy transition. The array protocols are very quick and simple, and we get a lot of extra information with CytoSure. The addition of the labelling kit has further streamlined sample throughput.”

Spencer Howell, Director of Cytogenetics at OGT, said: “I am delighted to announce the Genomic DNA labelling kit to accompany the second generation of CytoSure oligonucleotide arrays. By supplying arrays, reagents and analysis software, and with new products and array designs in development, we continue our commitment to providing aCGH analysis to cytogenetics laboratories around the world.”

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.OligonucleotidesOligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :
OGT Offers New Genomic DNA Labelling Kit for Cytogenetics Array