New Wound Making Tool Enhances Reproducibility and Efficiency

AutoScratch tool to facilitate 2D collective cell migration and invasion applications

3 Oct 2018
Frankie MacDonald
Administrator / Office Personnel

BioTek introduces the new AutoScratch™ Wound Making Tool to facilitate two dimensional (2D) collective cell migration and invasion applications. With a simple pushbutton operation, the AutoScratch automatically creates consistent scratches of equivalent size and area in confluent cell monolayers grown in 24- or 96-well microplate format. This eliminates variability found in manual scratch methods and increases the reproducibility necessary to analyze and normalize results across subsequent assays. The compact system easily fits into laminar flow hoods, while an integrated, multi-reservoir cleaning trough and pre-programmed method offer hands-free cleaning and decontamination of the interchangeable pin heads before and after use.

AutoScratch is an ideal companion tool for cell biology workflows incorporating BioTek’s Cytation™ Cell Imaging Multi-Mode Readers and Lionheart™ Automated Cell Imagers. In addition to kinetically monitoring cell migration and invasion, the automated instruments include Gen5™ software to automatically calculate wound width, wound % confluence and maximum wound healing rate.

BioTek Instruments, Inc., headquartered in Winooski, VT, USA, is a worldwide leader in the design, manufacture, and distribution of innovative life science instrumentation. Our comprehensive product line includes cell imaging systems, microplate readers, washers, dispensers, automated incubators, stackers and pipetting systems. These products enable life science research by providing high performance, cost-effective analysis and quantification of biomolecules, biomolecular interactions and cellular structure and function across diverse applications. BioTek espouses a "Think Possible" approach that sets the tone for fresh ideas, unsurpassed customer service and original innovations.

Agilent BioTek Lionheart LX Automated Microscope

Agilent Technologies

The Agilent BioTek Lionheart LX automated microscope is designed for affordability, offering an alternative to expensive, custom-built automated microscopes that are complex to learn and use. The compact, ocular-free hardware design is more comfortable to use and reduces ergonomic distress in operators. Along with Gen5 software, Lionheart LX enables Augmented Microscopy, which fully automates image capture, processing, and analysis. Operation is easy, load samples, start a run, and gather publication-ready images and quantitative data. Lionheart LX can increase your research output and reduce time and costs.

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Agilent BioTek Gen5 Software for Detection

Agilent Technologies

Agilent BioTek Gen5 software for Agilent BioTek multimode and single-mode microplate readers is an integrated tool for endpoint, kinetic, spectral scanning, and well area scanning. It controls all the functions of the plate reader and has powerful data analysis capabilities for a broad range of applications. Gen5 microplate reader software is also used to integrate BioTek plate readers to BioTek BioStack and other automated systems.

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New Wound Making Tool Enhances Reproducibility and Efficiency