New ELISA-like Assay for Hyaluronic Acid Launched

19 Jul 2017
Abigail Berry
Administrator / Office Personnel

Product news

AMSBIO announces the launch of a new hyaluronic acid quantification kit, based on a highly specific and tightly binding protein to detect and measure hyaluronic acid, also known as hyaluronan or HA.

This product is a competitive ELISA-like kit using a recombinant hyaluronic acid binding protein (rHABP) optimized to quantify HA polymers of average molecular weight greater than 7.4 kDa in samples such as serum, plasma and culture supernatant.

Hyaluronic acid (HA) is a glycosaminoglycan (GAG) with a simple structure that is widely found in the extracellular matrix, and abundant in synovial fluid, skin, umbilical cord, and vitreous bodies; contributing to tissue water retention and to cellular growth, differentiation, and migration. Because of its simplicity and ubiquity, HA is not immunogenic so classical immunological analysis has not been possible.

Recombinant HABP specifically detects hyaluronic acid (HA), binding to HA from all species and tissues. It does not cross-react with other GAG's or to DNA. Recombinant production means that rHABP offers intrinsically higher safety compared with animal-derived HABP.

Find further information on the new recombinant hyaluronic acid quantification kit here.

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ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.ImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.Recombinant ProteinsHuman SerumHuman serum is found in blood plasma. The protein is used in a variety of applications including tissue engineering, transplantation and cell therapy.ELISA
New ELISA-like Assay for Hyaluronic Acid Launched