Mitigate reruns and keep your PFAS samples flowing
Restek launches dual-bed Resprep PFAS SPE cartridges to streamline EPA Method 1633 workflows
20 Mar 2025Product news
Restek has introduced Resprep PFAS SPE cartridges that combine polymeric weak anion exchange (WAX) and carbon sorbents in a single, factory-packed cartridge, providing PFAS testing laboratories with a faster, simpler sample preparation workflow that supports compliance with U.S. EPA Method 1633. Designed for use in busy analytical labs worldwide, these cartridges help environmental, water, and food testing facilities meet stringent method detection limits while reducing hands-on time and variability.
What makes Resprep PFAS SPE cartridges different
Resprep PFAS SPE cartridges integrate both WAX and carbon sorbents into one dual-bed format, allowing laboratories to perform SPE extraction and carbon cleanup in a single step. This ready-to-use configuration removes the need for separate cartridges or manual packing, helping to simplify method development and routine PFAS analysis.
Each lot of WAX material used in the cartridges is tested for the 40 per- and polyfluoroalkyl substances (PFAS) listed in EPA Method 1633. This quality control step confirms that the sorbent does not introduce background PFAS and that method detection limits can be reliably achieved.
Streamlined PFAS SPE sample preparation
By combining extraction and cleanup in one cartridge, Resprep PFAS SPE products significantly streamline PFAS sample preparation. Laboratories can reduce the number of steps in their workflow, minimize potential sources of contamination, and improve throughput for high-volume PFAS testing.
The ultra-clean WAX and CarboPrep Plus sorbents used in the cartridges are engineered to support robust method performance. Their low background contribution helps laboratories meet method performance requirements for trace-level PFAS analysis in complex environmental and industrial matrices.
Optional factory-packed filter aid for challenging matrices
To further simplify sample preparation, Resprep PFAS SPE cartridges are available with an optional, factory-packed filter aid. This feature removes the need to manually pack glass wool, reducing both preparation time and variability between analysts or batches.
The integrated filter aid helps prevent clogging during extraction, enabling laboratories to process even dirty or particulate-rich matrices efficiently with a single extraction step.
Learn more about Resprep PFAS SPE solutions
For additional technical details on this two-in-one solution for PFAS SPE sample preparation, including guidance on method setup and performance, read more on Restek’s website.
Read more here.
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Frequently asked questions
How do Restek Resprep PFAS SPE cartridges support compliance with U.S. EPA Method 1633 for PFAS testing?
Resprep PFAS SPE cartridges from Restek are specifically designed to support compliance with U.S. EPA Method 1633 by combining polymeric weak anion exchange (WAX) and carbon sorbents in a single, factory-packed cartridge. Each lot of WAX material used in these cartridges is tested for the 40 per- and polyfluoroalkyl substances (PFAS) listed in EPA Method 1633 to confirm that the sorbent does not introduce background PFAS. This quality control step helps laboratories reliably achieve stringent method detection limits for trace-level PFAS analysis in complex environmental and industrial matrices.
What makes Resprep PFAS SPE cartridges different from traditional PFAS solid phase extraction solutions in environmental and water testing labs?
Resprep PFAS SPE cartridges differ from traditional PFAS solid phase extraction solutions by integrating both WAX and carbon sorbents into one dual-bed format, enabling laboratories to perform SPE extraction and carbon cleanup in a single step. This ready-to-use, factory-packed configuration removes the need for separate cartridges or manual packing, simplifying method development and routine PFAS analysis. The ultra-clean WAX and CarboPrep Plus sorbents minimize background contribution, reduce hands-on time and variability, and help environmental, water, and food testing facilities meet stringent method detection limits while improving throughput for high-volume PFAS testing.
How do Resprep PFAS SPE cartridges improve PFAS sample preparation workflows for challenging matrices in busy analytical laboratories?
Resprep PFAS SPE cartridges improve PFAS sample preparation workflows by combining extraction and cleanup in one cartridge, which reduces the number of steps, minimizes potential contamination sources, and streamlines processing in busy analytical laboratories worldwide. For challenging or particulate-rich matrices, these cartridges are available with an optional, factory-packed filter aid that eliminates the need to manually pack glass wool. The integrated filter aid helps prevent clogging during extraction, allowing laboratories to efficiently process dirty samples in a single extraction step while reducing preparation time and variability between analysts or batches.