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MilliporeSigma to Expand Oncology Research Offering at AACR 2017

Merck

Booth #931

3 Apr 2017
Lois Manton-O'Byrne, PhD
Executive Editor

Product news

MilliporeSigma have announced new innovations for oncology research at the American Association for Cancer Research Annual Meeting, April 2-5, in Washington, D.C. AACR attendees are encouraged to visit booth #931 to learn more about MilliporeSigma’s products and speak with company experts.

The expansion includes the launch of the new SMCxPRO™ instrument, which allows researchers to bind and quantify biomarkers in very low abundance, and profile cancer, and immune checkpoint proteins. The technology provides better outcomes for detecting various types of cancer and other diseases requiring ultra-high sensitivity and is less expensive than other technologies. It is just one product among a range of technologies that support in vitro models for discovery and in use in clinical settings.

“MilliporeSigma’s latest innovation is part of an entire suite of tools for predicting and characterizing cancer and driving therapeutics,” said Jason Apter, Head of Research Solutions Strategic Marketing & Innovation at MilliporeSigma. “Early cancer detection translates directly into options for patients and better outcomes for many types of cancer. We are committed to empowering scientists and researchers by giving them the technologies they need to develop new tools accelerate access to better health.”

MilliporeSigma offers dozens of products that predict cancer, including biomarkers, antibodies, as well as products for novel target discovery, including the Sanger CRISPR libraries. These CRISPR libraries are the first of its kind, providing a collection of individual clones designed to knock out every known human and mouse protein-coding gene using the CRISPR system. MilliporeSigma’s advancements in gene editing tools like CRISPR are helping to accelerate discovery and manufacturing of new treatments for difficult to treat conditions.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :In VitroIn vitro refers to experiments conducted outside living organisms, often in controlled lab environments such as petri dishes or test tubes. In vitro models are widely used in drug testing, cell biology, and disease research. Explore in vitro research tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.Cancer ResearchCancer research aims to understand the mechanisms of cancer development and progression to improve prevention, diagnosis, and treatment. From molecular biology to clinical trials, research spans a wide range of disciplines, including immunotherapy, targeted therapies, and drug discovery. Explore the best cancer research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.AACR 2017Gene EditingGene editing is the precise alteration to an organism's DNA, with CRISPR being the most well-known technique. It is used in a wide range of applications, including the development of disease models and gene therapy, and crop improvement. Browse our peer-reviewed product directory to find the best gene editing solutions, compare products, check reviews, and get pricing directly from manufacturers.Biomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.

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MilliporeSigma to Expand Oncology Research Offering at AACR 2017