Microsaic Systems to Launch Innovative Chip-based Mass Spectrometry Instrument at Pittcon 2013

4 Feb 2013

Microsaic Systems plc, the high technology company developing next generation mass spectrometry instruments, will showcase its new revolutionary chip-based technology for the first time on booth #2255 at PITTCON 2013, from March 17 - 21, 2013 at the Pennsylvania Convention Center, Philadelphia. Microsaic Systems is the only producer of mass spectrometry instrumentation using Micro-Electrical-Mechanical Systems (MEMS) technology. The significant and innovative advances in the new chip-based instrument, the Microsaic 4000 MiD, offers a redesigned unit with an even smaller footprint.

Microsaic Systems is the first and only company to have commercialized MS (mass spectrometry) technology on a chip based on MEMS technology originating at the highly regarded Optical and Semiconductor Devices Group at Imperial College London. The company’s breakthrough product, the 3500 MiD launched in January 2011, represented a step change in the ease of use and footprint of mass spectrometry. The instrument won an R&D 100 award from an independent judging panel and the editors of R&D magazine due to it being smaller, lighter, consuming less energy, easier to maintain and cheaper to run than conventional MS systems.

The Microsaic 4000 MiD is the culmination of over a decade of research, bringing together two high tech fields – chemical analysis and silicon micro-engineering – to make possible a transformative capability in detection. Its low operating cost and small footprint make the instrument deployable in a wide range of applications where mass spectrometry has not been able to reach - until now.

The next generation of the chip-based technology to make its US debut at Pittcon 2013 is now even smaller. As a result the Microsaic 4000 MiD fits even more comfortably into a standard lab fume hood, opening up further opportunities in the field of reaction monitoring. Users are able to increase the use of mass spectrometry in the lab, while benefiting from significant cost savings, owing to fewer necessary structural components such as gas generators and air conditioning. There are also sizeable savings with the use of ‘Plug and Play’ components which enable users to maintain the system themselves, resulting in less downtime and greater flexibility within the laboratory.

“With the premier launch of the Microsaic 4000 MiD and future plans for our growing portfolio of chip-based technology, the Microsaic exhibit at PITTCON will demonstrate how we work with and enable our customers to improve their laboratory operations,” said Colin Jump, CEO, Microsaic Systems. “Offering the smallest footprint in the market, the Microsaic 4000 MiD is a fully integrated, versatile, portable MS system designed for bench chemists. The core technologies are chip-scale versions of traditional mass spec components which can be interchanged rapidly by the user. This modular approach allows users to maintain the system without the need for expensive service contracts and time-consuming call-outs.”

The Microsaic 3500 MiD (Molecular Ion Detector)

Microsaic Systems

The Microsaic 3500 MiD (Molecular ion detector) is the world's smallest mass spectrometer, giving the chemist a compact, integrated system with no comprimise on performance. The 3500 MiD is the size of a single HPLC module with no floor pump or external PC. For the first time, chemists can have access to valuable MS data in the lab. The 3500 MiD is designed to integrate with existing HPLC equipment with no extra footprint and no infrastructure requirements (e.g. sound-proofing, AC). Extend the capability of your HPLC system with significant cost savings compared to a conventional MS system. Historically, MS has only been used for off-line analysis but the 3500 MiD is so compact can be used for on-line reaction monitoring in a fume-hood. Monitoring batch reactions in real time provides the chemist with vital reaction data which can be acted upon to maximise yield and/or minimize impurities. The 3500 MiD is also ideal for flow chemistry systems where MS data can be used for reaction optimisation. The system is portable with modular plug and play components for maximum application flexibility. Features of the 3500 MiD:•  Small footprint - fully integrated computer and vacuum system •  Stackable - size of standard LC module •  Quiet - no floor pump •  Unrivalled low power consumption •  Network ready - LAN interface and IP address •  Wireless keyboard and mouse, or remote access via LAN •  Intuitive, user-friendly Molecular iD software application •  Full data analysis suite based around total ion chromatogram (TIC) •  Full scan and selected ion monitoring (SIM) modes Applications of the 3500 MiD:•  In-line reaction monitoring (flow or batch) •  Mass selective detector for preparative and flash LC •  Process monitoring •  Analytical LC including Micro LC, Nano LC and HPLC

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