Major International Conferences to Hear About the Risks and Rewards of Synthetic Biology

12 Mar 2008

Product news

Representatives from Integrated DNA Technologies (IDT), a world leader in oligonucleotide synthesis, will be describing efforts to prevent the misuse of synthetic genomics, and presenting recent developments in RNAi research, at Analytica, Munich, 1-4 April and the RNAi World Congress, Boston, MA, 30 April – 2 May.

At Analytica, Damon Terrill, Sr. VP International Legal and Regulatory Affairs, will present on the cooperative efforts of government and industry to counter the potential misuse of synthetic genomics for harmful purposes. IDT is at the forefront of work by companies to develop improved gene sequence screening methods and more effective protocols for reporting and responding to possible security and safety risks. IDT’s leadership in the U.S. prompted the European Industry Association on Synthetic Biology (IASB) to invite IDT to discuss with Analytica attendees from around the world the benefits of a truly international approach.

At the end of April, the emphasis shifts to exciting new areas in basic scientific research with Dr Mark Behlke, IDT’s Sr. Vice President of Molecular Genetics & Biophysics and Chief Scientific Officer, presenting on the “Use of Dicer-Substrate siRNAs in Animal Research” and “Evolution of miRNAs in the Marsupial Monodelphis domestica”. New research carried out by Dr Behlke’s group reports on a number of interesting findings in RNAi research in several different model systems, including studies done in rats, mice and opossums.

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Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.OligonucleotidesOligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.RNA InterferenceRNA interference (RNAi) uses siRNA or miRNA for transcriptional silencing, gene knockdown and regulation of gene expression. RNAi requires chemical synthesis, introduction of DNA vectors into cells, an assay of RNAi effects and RNAi quantification or analysis. Consider target sequence selection, reagent preparation, controls, high specificity and effectiveness and low non-specific gene knockdown.
Major International Conferences to Hear About the Risks and Rewards of Synthetic Biology