LI-COR Introduces Custom Dye Labeling Services

8 Aug 2013

Product news

LI-COR now offers custom dye labeling and synthesis services, allowing researchers to contract with LI-COR to label proteins, antibodies, peptides, and small molecules. These services assist researchers with unmet needs that go beyond LI-COR's basic offerings.

Each LI-COR custom service offers the choice of a dye or quencher from the LI-COR portfolio of IRDye® infrared dyes and VRDye™ visible fluorescence dyes. In addition, LI-COR offers ROS (reactive oxygen species) probes, protocol development, and custom derivation of fluorescent dyes.

"By leveraging our years of experience in near infrared dye conjugation and fluorescence detection, we are able to expand our product offerings to include non-catalog items and projects," says Dr. Peter Johnson, LI-COR senior field application scientist and innovations manager.

LI-COR will provide a Certificate of Analysis (COA) at the request of the customer with every order that may include HPLC purity, Mass Spec and NMR analysis, extinction coefficient, final concentration, free dye determination and dye-to-protein ratio, depending on the requested synthesis or conjugation.

IRDye Infrared Fluorescent Dyes

LICORbio

IRDye Infrared Dyes and near-infrared (NIR) fluorescent imaging deliver enhanced sensitivity due to low background autofluorescence in the near-infrared region, therefore, giving a higher signal to noise ratios.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LabelingProtein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.ConjugationPeptidesPeptides are short chains of amino acids that play key roles in biological processes, including signaling, immune responses, and enzyme regulation. Peptide research is critical in drug discovery, diagnostics, and vaccine development. Browse our peer-reviewed product directory to find the best peptides and peptide-related products, compare options, check reviews, and get pricing directly from manufacturers.Dyes