Innova Biosciences Develops Site-Specific Bioconjugation Technology for Diagnostic Applications
27 Aug 2017Innova Biosciences, the inventor of the world's easiest to use antibody labeling kits, is pleased to announce the launch of a site-specific bioconjugation technology for attaching antibodies to gold nanoparticles.
Innova's core business is 'bioconjugation' – the joining of two molecules to form a hybrid 'conjugate'. Conjugates are used in diagnostic tests in hospitals and research labs around the world and in consumer items such as pregnancy test kits. Traditional methods for producing gold conjugates do not provide any control over the orientation of antibodies on the surface of the gold, which may lead to poor performance. Innova's latest conjugation kit, InnovaCoat® Gold-Hydrazide, allows antibodies to be conjugated via the Fc region, resulting in functional orientation on the nanoparticle surface and enhanced assay sensitivity.
Commenting on the launch of the new conjugation kit Dr Nick Gee, CEO of Innova Biosciences said: "In clinical diagnostics and point-of-care testing there is a desire for more sensitive detection systems to achieve earlier diagnosis and better treatment outcomes, for the benefit of human and veterinary health. This new product combines InnovaCoat® gold nanoparticle stabilization technology and antibody orientation technology to enhance the performance of antibody-based diagnostic reagents."
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Innova Biosciences - Conjugation Services
Innova Biosciences Ltd.Innova Biosciences – Antibody Conjugation Service Bio-conjugates can be challenging to optimise and time consuming to produce: 1. Too much conjugation may result in the target protein becoming inactive and insoluble. 2. Too little conjugation can result in weak signals. 3. Our competitors require milligrams of your precious material and have a 2 week process time. Fast & FAb™ Antibody Conjugation Service – Innova Biosciences take the hassle, time and effort out of making antibody conjugates. Using state of the art conjugation chemistry, Innova Biosciences have the ability to label microgram to milligram amounts of your antibody within 48 hours. Conjugate optimization (Micro-optimizer™) - Innova Biosciences uses its proprietary technologies to enhance the performance of conjugates. By creating an array of trial conjugates (10 formulations per label) at low microgram scale (10µg per formulation) combined with selection in the assay of interest, the best possible conjugate can be attained. PerfectSCALE™ - All conjugates produced using our micro-optimization™ technology can be scaled over many orders of magnitude without the need for extensive re-development of the process. The inherent simplicity of Innova’s technology means that exceptionally high yields are obtained, with minimal batch-to-batch variation, ensuring consistent performance.