Improve your cell viability with INTEGRA liquid handling solutions

INTEGRA Biosciences offers a range of electronic pipettes, pipetting robots and dispensers tailored to allow gentle pipetting for liquid handling tasks

16 Sept 2021
Rory Shadbolt
Publishing / Media

This equipment is designed to offer enhanced pipetting speed control, limiting the stress placed on cells during handling to improve cell viability. In the first of its cell culture series, INTEGRA tackles the challenge of cell viability, offering guidance for choosing the correct tools to optimize cell culture techniques.

Many vital stages in the cell culture workflow require handling or mixing solutions with a pipette but, if not done with care, this can lead to the shearing of cells at the orifice of the tip. Exposing cells to shearing forces can result in cell lysis and cell death, significantly reducing cell viability and reproducibility. Experts at INTEGRA have developed an extensive range of liquid handling products – from multichannel electronic pipettes to assisted robotic platforms – to help scientists reproducibly culture healthy cells. Electronic pipettes give scientists greater control during cell handling, ensuring consistent, clearly defined pipetting speeds to minimize shearing forces and reduce the influence of user technique as a potential source of variation. The company also offers its renowned GripTip pipette tips in various sizes and styles, including wide bore options with a larger orifice for cells to flow through, further reducing the shearing forces. These innovations are based on years of experience and an appreciation of customers’ needs, ensuring the company remains an all-around trusted supplier and partner for cell biologists.

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VIAFLO 384 – Electronic 24, 96 and 384 Channel Handheld Pipette

INTEGRA Biosciences

INTEGRA Biosciences’ VIAFLO 384 increases productivity of sample preparation in microplates and supports 24, 96 and 384 channel pipetting heads. VIAFLO 384 is used like a standard handheld pipette. It is hand-controlled but movements are supported by motors for an effortless workflow and precise targeting of the microplate wells. With a choice of ten interchangeable pipetting heads, the unit quickly adapts to any 24, 96, 384, or even 1536 well pipetting application in a volume range of 0.5 μl to 1250 μl.  VIAFLO 384 benefits from the innovative GripTip system. The special pipette tips, together with the unique tip fitting, form an integral system. It guarantees tips will not fall off during pipetting and provides a reliable sealing of every tip. VIAFLO 384 can be used for sample transfers from reservoir to plate, plate to plate or within plates. VIAFLO 384 Features and Benefits: VIAFLO 384 is used like a handheld pipette and has an intuitive user interface, freeing staff from training time. Pipetting heads can be changed for an optimal instrument adaption to different volume ranges, increasing accuracy and precision. The innovative GripTip system provides a reliable sealing of every tip and guarantees that tips will never fall off, providing safe and reproducible assay preparation. Various pipetting modes are available for increased productivity and application customization.

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VIAFLO 96 – Electronic 24 and 96 Channel Handheld Pipette

INTEGRA Biosciences

VIAFLO 96 increases productivity of sample preparation in microplates. It is used like a standard handheld pipette. It is hand-controlled but movements are supported by motors for an effortless workflow and precise targeting of the microplate wells. The working volume range of VIAFLO 96 can be quickly adapted to the application’s requirements by changing the pipetting heads. The 24 channel heads are available in the volume ranges 10-300 µl and 50-1250 µl and the 96 channel heads in the volume ranges 0.5-12.5 µl, 2-50µl, 5–125 µl, 10–300 µl and 50–1250 µl. VIAFLO 96 benefits from the innovative GripTip system. The special pipette tips, together with the unique tip fitting, form an integral system. It guarantees tips will not fall off during pipetting and provides a reliable sealing of every tip. VIAFLO 96 can be used for sample transfers from reservoir to plate, plate to plate or within plates. Features and Benefits:  • VIAFLO 96 is used like a handheld pipette and has an intuitive user interface, freeing staff from training time. • Pipetting heads can be changed for an optimal instrument adaption to different volume ranges, increasing accuracy and precision. • The innovative GripTip system provides a reliable sealing of every tip and guarantees that tips will never fall off, providing safe and reproducible assay preparation. • Various pipetting modes are available for increased productivity and application customization.

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GripTips for VIAFLO 96/384

INTEGRA Biosciences

When working with a 96- or 384-channel system such as the VIAFLO 96/384, it is essential that the pipette tips are reliably attached. Due to the unique design, the GripTip system ensures that the tips will never accidently fall off, even when performing a tip touch on the sidewall of a vessel. Pipetting with multiple channels into a well plate is a precision task. GripTips for VIAFLO 96/384 undergo an additional quality check for tip straightness, guaranteeing accurate pipetting in 96- and 384-well plates. Depending on the tip size, GripTips are packaged in two different tip boxes. Larger volume GripTips (300 µl, 1250 µl) are delivered in boxes of 96 tips. The smaller volume GripTips (12.5 µl, 125 µl) are filled in a space efficient 384-fold grid in XYZ boxes. These boxes house 4 times as many tips and feature the standard SBS-footprint. All tips are available in non-sterile, sterile or filtered sterile configuration. Features and benefits: • GripTips snap onto the tip fitting of the pipetting head, which prevents tips from falling off. • An additional quality check ensures that pipette tips are perfectly straight, enabling precise pipetting in multi well plates. • Filtered GripTips reliably protect the pipetting head against contaminations caused by aerosols.

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Improve your cell viability with INTEGRA liquid handling solutions