Flexible New Approach for Cell Based Assays

1 Mar 2012

Curiox Biosystems is pleased to display The DropArray™ System, offering researchers freedom from the constraints of conventional cellular assay platforms. The DropArray™ System expands the scope of research possible using primary cells, stem cells, suspension cells and more.

The novel science of the DropArray™ System allows for flexibility not available with standard cellular assay tools. It is the unique surface dynamic of this wall-less microwell plate system that makes it a powerful tool, suitable for any cell-based assay.

• Enabling wash-based assays using a broad range of cell types, including live suspension cells, with minimal cell loss.
• Requiring less than 500 cells per data point.
• Using only 2-3 ul of sample and reagents.
• Providing long-term cell culture of 3 ul samples for up to 2 weeks.

The DropArray™ System is a new approach to cell based assays. This unique platform will decrease the costs of your current cellular assays, increase the range of testing that can be performed with commonly used adherent cells and open doors to new possibilities for cells in precious supply or those more challenging to assay, such as weakly adherent or live suspension cells. Visit Curiox Biosystems at BOOTH 2126 to learn more about this revolutionary product line.

DropArray™ Accelerator HT200

Curiox

The DropArray™ Accelerator HT200 allows higher level of automation for researchers. It provides similar benefits to DropArray™ Accelerator LT100 with additional features required for our high throughput and screening customers. The HT200 is a fully automated washing instrument that can be easily integrated into existing liquid handling systems, and is compatible with traditional plate formats used in imagers and dispensers. It is used with the DropArray™ 384 plate and is applicable to academia, pharma and biotech for: •  High Content Screening •   RNAi screening •  Antibody & biomarker screening •  High throughput screening •  ELISA assays The HT200 represents a new standard of liquid handling proving improved fluidic design that allows for gentle washing of plates, resulting in minimal cell loss and improved experimental data. The images below demonstrate the immunostaining patterns of a MCF-7 breast cancer cell line on the DropArray™ 384 well plate, after 4 wash cycles using DropArray™ Accelerator HT200, carried out by our customer. Image A shows the staining patterns of the targeted endogenous protein expressed on the cell membrane. While image B shows the nuclear DAPI staining.

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DropArray™ Accelerator LT

Curiox

The DropArray™ Accelerator LT is the first in a series of products offered by Curiox. The Accelerator LT targets users in research labs performing ELISA and cell adherent assays. The DropArray™ Accelerator is a bench-top liquid handling station that automates the wash step in wash-based bioassays (bioassays that require a wash step in between addition of reagents) by eliminating conventional tedious and long drawn pipetting methods used for washing conventional plates. The whole 6 step wash on the takes less than 2mins using the DropArray™ Accelerator systems. Convenient and Highly Affordable Miniaturization The LT100 enables convenient and affordable miniaturization by automating the washing process of proprietary DropArray™ plates. The Accelerator LT100 supports two different formats of DropArray™ plates, the 48 and 96 well plates, while the Accelerator LT200 supports the 96 and 384 well plates. Each "well" functions effectively and similarly to a microtiter plate well, only, at a much smaller volume of 2-3 µL. Improved Efficiency in performing assays Specifications for DropArray™ Accelerator LT100/LT200: •   Operating Voltage/Hz: 100-240 V (manual select), 50/60 Hz •   Max Power Requirement: 156 VA •   Physical size: 46 cm x 44 cm x 33 cm •   Weight: 13.5 kg

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Flexible New Approach for Cell Based Assays