Fast, easy, and affordable multiplex cell analysis solutions for apoptosis, viability, toxicity, growth and more...

For researchers who want to do cell cycle research at their benchtop, Guava Cell Cycle assay can be used for measuring G0/G1, S, and G2/M phase distributions. Based on the established method of whole-cell staining with propidium iodide (PI), Guava's cell cycle assay is easy to learn. Guava Cell Cycle software includes markers that can be set for quick assessment of G0/G1, S, and G2/M phase cell cycle percentages as data is being collected for rapid screening of compounds. Results are automatically exported to a spreadsheet; raw data can also be exported to third-party software for cell cycle analysis using modeling algorithms. Whether you are a researcher exploring the mitotic pathway, or evaluating novel compounds for cancer therapies, you will appreciate the ease and convenience of doing cell cycle studies, right in your lab.

Apoptosis, or programmed cell death, is a highly regulated pathway that is important in normal developmental processes as well as many diseases. Cells undergoing apoptosis are identifiable by a number of characteristics, including changes in mitochonrial membrane potential, transport of phosphatidylserine (PS) to the membrane surface, activation of caspase proteases, and DNA fragmentation in the nucleus. Guava offers four apoptosis assays to assess these markers of early-, mid- and late-stage apoptosis: Annexin V binding (Guava Nexin assay) Multiple caspase activity (Guava MultiCaspase assay) Caspase 3/7 or 8 Activation DNA strand breakage (Guava TUNEL assay) For monitoring changes in mitochondrial membrane potential (Guava MitoPotential assay) Engineered for use on the Guava PCA systems and requiring only microvolume cell samples, all three assays provide superior discrimination between apoptotic and non-apoptotic cells. When used together, the Guava assays provide detailed profiles of cell populations in various stages of apoptosis. The no-wash, mix and read Guava Mitopotential and Guava Nexin assays can be especially powerful for rapid screening in 96-well microplates. Each assay uses proprietary Guava software, and reagent kits optimized for use with the Guava system.

Guava Technologies' ViaCount assay is revolutionizing the way cell counting and viability assessment are done in today's laboratories. Fast, automated, and highly reproducible, the Guava ViaCount assay addresses many of the difficulties of conventional cell counting and viability assessment methods. The Guava ViaCount assay provides: Cell counts up to ten times faster than manual counting, in a convenient turnkey assay. Accurate, reproducible counts with very low density cell samples or small sample volumes. Absolute cell counts, viability assessments and apoptotic cell counts in a single measurement. By providing data on all these cell populations in a single measurement, the Guava ViaCount assay enables a more precise evaluation of culture conditions and viable cell populations so you can best optimize culture conditions. Flexibility for many cell types. Accurately counts adherent, clumpy and even non-mammalian cells, such as insect cell lines. More experimental consistency. These precise, accurate cell counts can provide more consistency in experiments that require accurate viable cell counts for success, such as ELISpot, cell-based fluorescence assays or cytokine production assays. The Guava ViaCount assay uses proprietary easy-to-use Guava software, and reagent kits optimized for use with the Guava PCA and PCA-96 systems. Guava ViaCount is fast becoming the method of choice for monitoring cell culture or bioreactor conditions and cell count/viability assessments.