Current methodologies for drugs of abuse whole blood testing

19 Aug 2025

Extraction of drugs of abuse panels from whole blood samples can be challenging, especially when analyzing a broad panel of analytes from different classes. This white paper studies the analysis of 56 common illicit drugs in whole blood, focusing on various aspects of sample preparation, including pre-treatment of whole blood samples, extraction techniques, and automation using Biotage® Extrahera sample preparation workstation.

Biotage® Extrahera™ Automated Extraction System

Biotage

Biotage® Extrahera™ is an easy-to-use automated system for SLE, SPE, PLD, and PPT in plate or column formats. With flexible volume handling, dual-flow positive pressure, and no programming required, it streamlines workflows, reduces solvent use, and frees analysts for higher-value tasks while delivering reproducible, GLP-compliant results.

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