Corning Expands Microcarrier Product Line for Bioprocess Scale-up

15 Sept 2013

Corning Incorporated today announced it has expanded its microcarrier product line for bioprocess scale-up with the addition of four new Corning® Microcarriers for large-scale vaccine and cell therapy manufacturing.

Corning Life Sciences will showcase its latest microcarrier innovations in booth #800 at the upcoming Bioprocess International Conference in Boston, Sept. 16-19.

The four new microcarriers are offered with various surface treatments and coatings to enhance cell attachment, helping maximize cell yield and viability:

• Corning Synthemax® II Coating. The unique substrate creates a synthetic surface on the microcarriers for stem cell expansion. Low-concentration microcarriers are available for mesenchymal stem cell (MSC) applications. High-concentration microcarriers are available for induced pluripotent and stem cell (iPS/ES) applications.
• Corning CellBIND®. This surface treatment infuses the surface of the microcarriers with oxygen to improve cell attachment.
• Positive charge surface treatment.
• Collagen coating.

“Researchers today are pressed to more efficiently and effectively scale up their bioprocess production,” said Ken Ludwig, business manager, Bioprocess and Cell Therapy, Corning Life Sciences. “These newest Corning advancements build on our existing microcarrier product line and all of our scale-up technologies to provide a more advanced and broader range of options to do just that.”

The latest Corning microcarrier offerings are sterile, ready-to-use, and available as closed-system solutions. They can be used directly with bioreactors, are nonpyrogenic, and are made with USP Class VI polystyrene material to provide a consistent platform for improved results. The new products extend Corning’s ongoing scale-up offerings, joining Corning’s line of CellSTACK® and HYPERStack® scale-up vessels, the full range of spinner flasks, and advanced cell culture media solutions.

Corning Life Sciences will also feature Corning® Mini Bioreactors at the Bioprocess International Conference. Announced in April 2013, the Corning Mini Bioreactors consist of a Corning® 50 mL Centrifuge Tube with a vented cap, and are ideal for high-throughput process optimization for suspension cell culture.

Through acquisition and ongoing investment in research and development, Corning now offers a more comprehensive range of premium, innovative laboratory products, and solutions for a wide spectrum of life science applications. Corning’s trusted, quality brands, backed by technical expertise, provide researchers with better ways to advance their research from the beginning of their process to the end. The family of brands includes Corning®, FALCON®, PYREX®, Costar®, Axygen®, Gosselin™ and Corning cellgro®.

Corning Life Sciences continually brings new and innovative laboratory technologies to researchers worldwide and helps customers succeed by providing innovative, high-quality products and services including polymer science, biochemistry and molecular biology, glass melting and forming, surface modification, and characterization science.

Polystyrene CellSTACK® - 40 Chamber with Vent Caps, 2 per Case

Corning Life Sciences

Has 25,440cm² cell growth area Two 26mm diameter filling ports allow direct access to chamber bottom providing greater flexibility for sterile filling and emptying by pouring, pipetting or via tubing in a fully closed system Standard 33mm threaded caps have 0.2 µm pore nonwettable membranes sealed directly to the caps to allow gas exchange Optional 33mm threaded caps are available with integrally sealed chemically resistant, heat sealable flexible tubing to allow direct transfer of media and cells USP Class VI polystyrene provides excellent optical clarity and mechanical strength Sterilized by gamma radiation and nonpyrogenic 100% leak tested prior to shipping

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