Corning Expands Drug Discovery Offering at SLAS2016

Corning Life Sciences vice president and general manager to showcase growing portfolio

13 Jan 2016
Lynsey Forsyth
Post Doc / Research Fellow

Corning will feature innovations and laboratory solutions including:

The Corning® spheroid microplate - click here

Corning glass-bottom and cyclic olefin copolymer (COC) film-bottom microplates for high-content screening - click here

The new Corning® HepatoCells - click here

The recently launched Axygen® automation-compatible PCR microplate - click here

“Corning products help our customers optimize their assays and streamline high throughput screening,” said Richard Eglen, Ph.D., vice president and general manager, Corning Life Sciences. “Corning is leveraging its capabilities in precision forming and its life sciences industry experience to help researchers focus on the discovery and development of new ways to treat disease. And, we’re committed to developing innovative solutions that accelerate discovery.”

The 96-well and 384-well spheroid microplates feature a novel and proprietary design ideal for generating and analyzing 3D multicellular spheroids in a single, automation-friendly microplate. This design features Corning’s ultra-low attachment surface and a black opaque microplate body that shields each optically clear well from crosstalk. Together, these features enable users to reproducibly form a single, unique spheroid in each well and successfully perform assays in the same plate.

“3D cell culture is an important emerging application area where broad adoption in screening has been limited by cost and complexity of the assays,” said Keith R. Olson, Ph.D., Corning Cell Culture business director. “Corning spheroid microplates allow our customers to reduce the number of steps in generating 3D multicellular spheroids and operate in a screening environment more effectively.”

Corning now provides a full portfolio of glass-bottom and COC film-bottom microplates that are ideal for high-content screening and imaging applications. These high-optical quality microplates provide industry-leading flatness that reduces autofocus time, increases throughput, and improves high-content screening assay performance.

The new Axygen® automation-compatible PCR microplate offers a unique design to prevent plate warping and minimize evaporation during thermal cycling. A rigid frame with a small split sustains heat transfer during cycling without distorting its shape. The plate is the latest addition to a large portfolio of automation consumables including the extensive range of Axygen automation tips for liquid handling.

New Corning® HepatoCells offer a renewable alternative to primary hepatocytes that is consistent and convenient. This exciting new product delivers robust induction response for major Cytochrome P450 (CYP) enzymes combined with the reliability and reproducibility benefits of a homogeneous cell line.

Corning will also feature additional solutions for lab automation, drug screening, and cancer research at SLAS.

During the SLAS2016 meeting, Eglen will be appointed president of SLAS after serving the past two years as an officer on the board of directors. Eglen was elected to the board of directors in 2014 in recognition of his achievements and leadership in the life science industry and the SLAS scientific community.

To learn more about Corning Life Sciences products, please contact a customer service representative at 1-800-492-1110 FREE, toll free in the United States; (+1) 1-978-442-2200 internationally; or visit www.corning.com/lifesciences.

Corning® 384-well Black/Clear Round Bottom Ultra-Low Attachment Spheroid Microplate, Bulk Packed 10 per Bag, with Lid, Sterile

Corning Life Sciences

Ultra-Low Attachment microplates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment Surface minimizes protein absorption, enzyme activation and cellular activation Surface is noncytotoxic, biologically inert and nondegradable Sterilized by gamma irradiation Black wall microplates have low background fluorescence, minimal light scatter and reduced crosstalk Opaque walls to prevent well-to-well crosstalk Can be used for both top and bottom reading instruments Bulk packed 10 per bag Novel well geometry aids formation of spheroids in center of well Optically clear round bottom with black opaque microplate body

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Corning® 96-well Black/Clear Round Bottom Ultra-Low Attachment Surface Spheroid Microplate, Bulk Packed, with Lid, Sterile, 10/Bag

Corning Life Sciences

Ultra-low attachment surface with covalently bonded hydrogel that minimizes cell attachment, protein absorption, enzyme activation and cellular activation The surface is noncytotoxic, biologically inert and nondegradable Round bottoms with 300 µL total volume Recommended working volumes of 0.075 to 0.30 mL Sterilized by gamma radiation Novel well geometry aids formation of spheroids in center of well Optically clear round bottom with black opaque microplate body

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Axygen® 96-well Automation Compatible Polypropylene PCR Microplate, Half Skirt, Clear, Nonsterile

Corning Life Sciences

Axygen® automation-compatible PCR microplate features a rigid frame with a small split that sustains heat transferring during and post thermal cycling without distorting its shape. The polypropylene plate also features raised rims around the wells to provide tight sealing to minimize heat evaporation. Compatible with most major thermal cyclers, sequencers, and automation platforms, the plate provides optimal performance for downstream applications, including high throughput screening.Remains flat during and post thermal cyclingRaised well rims help reduce heat evaporationClear wells, visible grid for easy sample loading and trackingUltra-thin and consistent wall thickness for easy and consistent heat transferSuitable for standard and real-time PCRSingle notch cornerSBS footprintManufactured from polypropyleneRNase-/DNase-freeNonpyrogenicNonsterileCompatible with major automation platforms, thermal cyclers, and sequencers

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