Biotage Launches New Fully Integrated Mass Directed Flash System, Isolera™ Dalton

Biotage, a leading global supplier of solutions and technology for analytical, medicinal and peptide chemistry, announces the launch of the new Isolera™ Dalton - a fully automated miniaturized mass directed flash purification system. The new system raises the bar for flash purification by integrating, for the first time, a miniaturized mass detector and an advanced flash chromatography system into one commercially available platform.

The mass detector and Isolera™ Spektra flash purification system are seamlessly integrated via the Isolera™ Dalton Nanolink unit, an intelligent sampling device which handles all fluids and synching calculations between the two units. Isolera™ Dalton easily fits inside a standard fume hood, requires no external pumps and is capable of both normal and reverse-phase separations, so it is completely compatible with the diverse purification needs of the modern research laboratory.

“Compounds are identified in real time during purification and this informs the flash fractionation process, enabling the correct product to be collected by the system. The system automatically accommodates different column sizes and flow rates, overcoming major issues with simple splitter-based systems. Isolera™ Dalton significantly reduces the number of steps required to purify and confirm a target compound, thus improving workflow and increasing confidence that chemists have synthesized what was intended. Quite frankly there is nothing else like it on the market today or that even comes close” says Dr Sunil Rana, Global Product Manager, Biotage.

The instrument uses a wizard-based approach to method development, simple on screen prompts guides chemists through the system; even those whose expertise or priorities lie in compound synthesis rather than analysis.