Automated microscopic imaging solution in climate-controlled environment

The new automated microscopic imaging solution in an incubator from Memmert in cooperation with Opto GmbH offers a complete solution for a continuous monitoring of samples under controlled climatic conditions, without the need to remove specimens from the device. The combination of intelligent imaging and ambient monitoring enables a precise automated evaluation of samples whilst minimizing the risk of human error and providing reproducible results.

With round-the-clock automation, controlled environmental conditions and availability of digital data, the system provides an efficient solution for long-term studies and quality assurance purposes. The devices can be used for a range of applications, including: the pharmaceutical industry and medical sector, research in the biological, chemical and food sectors, industrial material and component testing, and for different quality tests in demanding manufacturing processes.

Automated microscopic imaging – inside the incubator

The solution is based on an intelligent imaging module from Opto, that is capable of capturing high-resolution microscopic images of samples from within the Memmert incubator – even during ongoing tests. This seamless integration of imaging and precise climate control enables a continuous and reliable monitoring of samples.

Advanced AI-supported image analysis

The generated images are automatically transferred to an advanced software developed by Opto. Using artificial intelligence, the system converts the raw data into false-color images and analyses the development of the specimen. This, for example, makes it possible to document cell confluency – the seamless coverage of the surface of a culture dish by adherent cells – over a period of time with precise percentage values. The images are saved along with timestamp, details of ambient conditions and AI-supported software evaluation. The door of the device does not need to be opened for microscopic examination during the ongoing test. This eliminates the risk of sample contamination and fluctuations in temperature.

Benefits of this integrated system:

• Round-the-clock automation – no manual handling required.
• Avoidance of ambient fluctuations during the monitoring process thereby ensuring a consistent and stable environment.
• Minimization of the risk of contamination by eliminating the need for sample removal.
• Reduction in the level of human error resulting in improved quality assurance.
• Possibility for automatic sample evaluation thus saving time and increasing efficiency.
• Assurance of reproducible results, crucial for long-term studies and quality control processes.
• Digital availability of all data enables easy archiving, tracking and analysis for research and quality assurance purposes.

Technical details of the digital microscopes

Opto digital microscopes (imaging modules) bring an unprecedented level of user-friendly and easy-to-integrate imaging performance to any production environment – from measuring machines and inspection systems to bio-imaging instruments.

Each module comes complete with its own SDK and comprehensive free image capture software, so it can be easily integrated into any existing network or system.

• High-resolution, perfectly matched optical designs with latest image sensors and high-performance LEDs in a compact aluminium housing.
• USB3 or GigE interface with compatibility to most image processing libraries.
• Ultimate image quality, easy integration, guaranteed performance in any application.
• Powerful imaging with simple plug-and-play functionality.
• Enhanced image quality thanks to perfectly matched component selection.
• Robust aluminium block design with different mounting options. Includes OptoViewer and various application plug-ins.
• Software integration tools: C/C++ OptoSDK, NI LabVIEW Toolkit, NI Vision Builder Plugin.

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