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Akoya Biosciences introduces PhenoCode Discovery Panels to simplify PhenoCycler-Fusion workflow

Akoya Biosciences
17 Apr 2023
Jemima Arnold
Editorial Assistant

Industry news

Akoya Biosciences, lauched its PhenoCode™ Discovery Panels, which simplify spatial biology workflows performed on the Akoya PhenoCycler-Fusion platform, at the American Association for Cancer Research (AACR) Annual Meeting 2023 in Florida, USA.

PhenoCode Discovery Panels are designed to advance cancer research by enabling thorough interrogation of tumors and the surrounding tumor microenvironment. Each of the ready-to-use, modular panels include biomarkers that can answer key biological questions related to immune profiling, lymphocyte profiling, tissue architecture, and immune activation and proliferation. Upfront assay development and validation time is significantly reduced, promising accelerated spatial discovery by 3x compared to standard workflows.

“The PhenoCode Discovery Panels further streamline and simplify the workflow on the PhenoCycler-Fusion System, offering new avenues of exploration for existing customers and paving the way for researchers who want to leverage this powerful technology for the first time,” said Brian McKelligon, CEO of Akoya. “These panels are an important part of the spatial biology ecosystem which Akoya has established and continues to expand. Our vision is to offer a comprehensive suite of panels for multiple applications. We expect to launch additional PhenoCode Discovery Panels for protein biomarkers throughout 2023 and 2024, and introduce panels for RNA in the second half of this year.”

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Assay AssemblyAssay Assembly is technique used in drug discovery to develop assays to test the cytotoxicity, genotoxicity, or other activities of a compound on a cell. Assay assembly requires chip assembly, a delivery system and a detection and analysis method. Beneficial features of assay kits or automated systems include high-throughput, high speed and sensitivity and low signal to noise ratio.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.LymphocytesAACRThe American Association for Cancer Research (AACR) is a leading organization focused on cancer research and treatment. It provides a platform for scientists, healthcare professionals, and industry leaders to share knowledge and collaborate in the fight against cancer.

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Akoya Biosciences introduces PhenoCode Discovery Panels to simplify PhenoCycler-Fusion workflow