10x Genomics acquires Proteintech Genomics to expand single cell proteomics capabilities

10x Genomics, Inc. has acquired Proteintech Genomics, a division within Proteintech Group. Proteintech Genomics specializes in developing high-plex proteomic solutions for single cell and spatial applications on 10x Genomics platforms. The acquisition strengthens 10x Genomics’ position in single cell and spatial biology by expanding its proteomics capabilities and supporting integrated multiomic analysis.

Advancing single cell and spatial biology platforms

The acquisition builds on 10x Genomics’ broader vision to enable multimodal biological analysis across the company’s single cell and spatial platforms, including protein capabilities planned for the recently launched Atera platform. By combining transcriptomic and proteomic-based measurements, researchers can gain complementary insights into cellular identity, state and function.

These integrated approaches have helped advance discovery across immunology, oncology, neuroscience and broader cell biology research. However, many researchers currently rely on multiple vendors and workflows to harmonize RNA and protein analysis in single cell experiments.

The integration of Proteintech Genomics’ technologies into 10x Genomics platforms is intended to streamline these workflows and support more comprehensive multiomic studies.

Proteintech Genomics’ role in integrated RNA and protein analysis

Proteintech Genomics brings differentiated technologies, including its Human Discovery Panel, the largest antibody-based single cell protein panel designed to support integrated analysis of intracellular proteins, cell surface proteins and transcriptomic profiles within sequencing-compatible workflows. The Human Discovery Panel is compatible with Flex chemistry, including the Flex Apex assay.

Proteintech Genomics’ protein panels were purpose-built for 10x Genomics single cell workflows and are already used by many researchers to simultaneously analyze RNA and protein. From its inception, Proteintech Genomics focused on the combined power of RNA and protein measurements.

Enabling richer views of cellular state

The combination of 10x Genomics’ scalable single cell and spatial biology platforms with Proteintech Genomics’ advanced capabilities in protein detection is intended to enable richer, more predictive views of cellular state. By bringing scalable protein measurements into single cell and spatial biology, the acquisition supports the development of more comprehensive models of complex biological systems.

Michael Schnall-Levin, Chief Technology Officer, Chief Strategy Officer and Founding Scientist of 10x Genomics, said, “We believe the future of biological analysis will increasingly integrate transcriptomic and proteomic information at the single cell and spatial levels. The acquisition of Proteintech Genomics expands our capabilities in proteomics and supports our broader vision for richer multiomic approaches to understanding biology.”

Dr. Kristopher Nazor, CEO of Proteintech Genomics, said, “Because our technologies were designed to integrate with 10x workflows, joining the 10x team feels like a natural next chapter. We are excited about the opportunity to accelerate innovation together and expand access to integrated multiomic approaches for researchers around the world. Single cell and spatial biology has always promised a more complete picture of cellular state - protein and RNA together, at scale, across tissues. We’re finally in a position to deliver on that promise.”

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