The Simultaneous Collection of MRM and MS/MS Data to Detect and Quantify Drug Metabolites

Acquire, Analyze, Manage, and Share Mass Spectrometry Information MassLynx™ Software increases the speed at which you can convert your sample data into valuable knowledge. It provides you with the fundamental platform to acquire, analyze, manage, and share your mass spectrometry information. MassLynx intelligently controls any Waters mass spectrometry system, from sample and solvent management components to mass spectrometer and auxiliary detectors. MassLynx Software may acquire nominal mass, exact mass, MS/MS and exact mass MS/MS data. MassLynx’s Sample List is the core of the system. It maintains and consolidates the data on all of your samples. You also initiate any activities related to your sample from the Sample List. This "sample centric" approach simplifies the interaction with your LC/MS or GC/MS system, acquired data and processed results. Process Application-specific Data MassLynx Software features general purpose and specialized Application Managers that provide information for your specific MS analyses and data. Two come standard with MassLynx: QuanLynx™ for automated quantification included as standard with MassLynx OpenLynx™ for qualitative screening and identification Optional Application Managers can perform: Targeted quantitative analysis Mass-directed purification Metabolite identification Deconvolution of complex chromatograms Metabonomics & metabolomics Protein identification and protein characterization

Waters Xevo™ TQ MS provides the ultimate in quantitative capabilities for your most demanding applications and your most complex sample matrices. It is a highly advanced tandem quadrupole mass spectrometer designed to enable uncomplicated access to superior HPLC and UPLC®/MS/MS performance, delivering the highest levels of sensitivity, selectivity, robustness, speed, and accuracy. Waters Xevo TQ MS is equipped with unique collision cell technology (ScanWave™) to provide new enhanced spectral LC/MS/MS data acquisition capabilities. Unlike conventional tandem quadrupole mass spectrometers, the Xevo TQ MS is designed not only to provide the very best quantitative data, but also to provide you with superior spectral MS/MS information. Xevo TQ MS offers you much more versatility in a single instrument platform that is adaptable to a variety of different UPLC/MS/MS applications both quantitative and qualitative: bioanalysis, ADME screening, food safety, environmental monitoring, forensic, and more. Features: Automated system set up and system checks for simple access Automated instrument optimization and quantitative method development tools for ease-of-use The latest innovations in high efficiency, robust, easy-to-use ZSpray™ atmospheric pressure ion source technology Versatile range of ionization options, including multi-mode ionization capability in a single run Unique, innovative T-Wave™ and ScanWave enabled collision cell technology Footprint that sits easily on your laboratory benchtop Dedicated application managers for your specialized analytical requirements

Xevo TQ-S tandem quadrupole mass spectrometer - designed for the most demanding quantitative UPLC/MS/MS applications. The ultimate in tandem quadrupole performance allows you to achieve unrivalled sensitivity and robustness, available to everyone due to the accessibility of the Xevo platform. The Xevo TQ-S gives you class leading sensitivity and robustness, qualitative information when you need it most and accelerated method development for sensitive and robust methods. Reducing complexity, increasing ease of use, and ensuring the correct result every time.