Streamlining Current Approaches for Extractable Analysis Utilizing Waters MV-10 ASFE and ACQUITY UPC2 Systems

Convergence Chromatography with the ACQUITY UPC² System Bring streamlined workflow, expanded selectivity, and an orthogonal technique to your laboratory. Convergence chromatography (CC) is a broad-based, complementary analytical platform that is taking its place alongside of LC and GC as one of the three essential separation technologies for modern laboratory analysis. This technique provides another, reliable choice as an analytical platform that is orthogonal to reversed-phase LC (RPLC), while significantly streamlining the entire analytical workflow. In convergence chromatography, the separation is achieved by manipulating the density and composition of a supercritical fluid-based mobile phase. Because of the very high diffusivity of the mobile phase, can be achieved. Additionally, the diversity of stationary phase and mobile phase (co-solvent) options provides access to the largest selectivity space available to any separation technique. The ACQUITY UPC² System is a holistically designed UltraPerformance Convergence Chromatography (UPC²) system that utilizes liquid CO2 as the primary mobile phase. The system leverages the chromatographic principles and selectivity of normal-phase chromatography while providing the ease-of-use of RPLC, enabling you to address routine and complex separations challenges. ACQUITY UPC² System: Discover what's been missing from your analytical toolbox With the ACQUITY UPC² System, scientists can now separate, analyze, and understand compounds that have challenged all other LC and GC technologies including: Hydrophobic and chiral compounds Lipids Thermally-labile samples Polymers It's also the perfect complement to MS due to its low solvent load and high resolution, narrow peaks and fast separations. ACQUITY UPC² System Features: Compressed carbon dioxide (CO2), the primary mobile phase, is less costly and less toxic than liquid mobile phases or carrier gases. Variable volume injection delivers 0.5 µL to 10 µL as well as the ability to match column and injection volume with minimal sample loss and need to change loops. Higher throughput and productivity allows you to analyze more samples per day with faster re-equilibration of columns and shorter cycle times, increasing laboratory productivity. Co-solvent and column switching provides flexibility in method development for faster solvent screening and faster column screening.

The Waters® MV-10 ASFE™ System is the first supercritical fluid extraction (SFE) system offering accelerated, multi-vessel sample extraction, resulting in a faster, greener, more selective alternative for analyte extractions from a wide variety of sample matrices. Whether your workflow requires enriching target analytes for analytical purposes, stripping unwanted material from a product, or collecting valuable essential oils from natural products, the MV-10 ASFE System is the most efficient extraction tool available. This system allows you to: •  Extract samples from up to 10 extraction vessels in a semi-automated fashion •  Accelerate throughput •  Lower operating costs compared to traditional hydrocarbon-based solvent extraction systems. •  Use a green alternative to normal phase solvents, supercritical CO2, which is non-toxic, non-flammable, and environmentally compatible. System features: •  Uses environmentally friendly CO2 instead of toxic organic solvents •  Improved extraction efficiency •  Better selectivity •  Increased speed •  Higher yield •  Reduced operating costs •  ChromScope™ Software makes routine analysis, reporting, and fraction collection easy with an intuitive user-friendly interface

The Empower Chromatography Data System is Waters’ compliance-ready chromatography data software (CDS) for advanced data acquisition, processing, and reporting that simplifies the management of chromatography test results.