Application Note: Real Time Calcium Flux Measurements in iPSC
27 August 2014

Achieving an approval for a new drug involves extensive pre-clinical testing to predict potential unwanted side effects that may be caused by taking the drug candidate. In this application note we will present a 3D cell culture model using cardiac myocytes derived from human induced pluripotent stem cells (iPSCs), to analyze compound induced changes in calcium handling, which can indicate potential side-effects of drug candidates.