Rapid Screening & Optimization of Crystallization Conditions of the Bacterial Periplasmic Binding Protein, HbpA Role as a Glutathione Import Protein

Glutathione is one of the major antioxidants/redox molecules in most aerobic cells, playing an important role in cell metabolism, differentiation, proliferation, and apoptosis. The reduced form of glutathione (GSH) is required for the detoxification of drugs and reactive compounds of both endogenous and exogenous origin, the delivery of its constituent amino acids to other tissues and the secretion of hepatic bile.