Application Note: Polar Basic Drugs in Environmental Samples; Improved Analysis Using a New High Efficiency UPLC Column for HILIC
7 October 2014

The purpose of this application note is to demonstrate the CORTECS UPLC HILIC Column for determination of highly polar basic compounds. In this application, a number of these compounds are determined in a spiked river water sample. Sample preparation was performed using the EPA 1694 method modified for use with a smaller sample volume and a smaller.