Application Note: Multi-element Analysis of Biological Materials by ICP-MS using Alkali Dilution
1 May 2017

Inductively Coupled Plasma – Mass Spectrometry (ICP-MS) is the instrument of choice when it comes to elemental analysis of biological materials including urine, whole blood, plasma and serum. The fast, multi-element capability of the technique and wide dynamic range are key benefits that allow the measurement of major, minor, essential and toxic elements, covering the concentration range from sub parts-per-trillion (ppt) to percent levels in a single analysis.  This application study evaluates an alkali sample preparation procedure that allows for the broadest range of elements to be measured accurately and precisely for different biological samples using a single, external calibration.