Application Note: Monitoring Receptor Ligand Binding in Living Cells
19 August 2015

This application will demonstrates how a cAMP BRET biosensor can be used to monitor ligand binding with the help of the CLARIOstar microplate reader. Bioluminescence resonance energy transfer (BRET) is an established method to study protein-protein interactions. Most of the research focuses on GPCRs as these receptors play an important role in finding new drug candidates.