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Fast and Sensitive UPLC/MS(MS) Determination of Diquat and Paraquat in Drinking Water

8 Apr 2013

Paraquat and diquat are quaternary ammonium herbicides. Because these compounds are potentially toxic to wildlife and to humans, groundwater and surface water samples are monitored to assure that residue levels meet safety standards. This application note describes an optimized method for determination of paraquat and diquat in drinking water using an Oasis WCX cartridge for SPE prior to fast and sensitive UPLC/MS(MS) analysis.

ACQUITY UPLC H-Class PLUS Bio System

Waters

The ACQUITY UPLC H-Class PLUS Bio System delivers the benefits of UPLC's resolution, sensitivity, and throughput in a system purpose-built for the analysis of proteins, peptides, nucleic acids, and glycans.

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BEH (Ethylene Bridged Hybrid) Particles for ACQUITY UPLC

Waters

The 1.7 µm Ethylene Bridged Hybrid [BEH] particle is one of the key enablers behind UPLC® technology.It is available in three different pore sizes [130Å, 200Å and 300Å] and several bonded phases for reversed-phase and hydrophilic interaction chromatography and is applicable from small molecule to large biopharmaceutical analysis. Due to the intrinsic chemical stability of hybrid particle technology, a wider usable pH range [pH 1-12] can be employed, enabling a versatile and robust separation technology for method development. BEH particle technology is available in HPLC particle sizes [2.5, 3.5, 5 and 10 µm] in the XBridge® family of HPLC columns, enabling seamless transfer between HPLC and UPLC technology platforms.

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Fast and Sensitive UPLC/MS(MS) Determination of Diquat and Paraquat in Drinking Water