Application Note: Determination of 1, 4-Dioxane in Drinking Water by Solid Phase Extraction (SPE) and Gas Chromatography/Mass Spectrometry (GC/MS) with Selected Ion Monitoring (SIM)
25 April 2013

1, 4-dioxane (CASRN 123-91-1) referred to as dioxane, is a highly water soluble non-biodegradable ether. This note presents a GC/MS method for the determination of this analyte in drinking water. Two options are featured. Option 1 is designated for sample volumes of ≤ 500 mL. Option 2 is designated for sample volumes of ≤ 100 mL. Both products can be used with most automated systems.