Application Note: Brightfield and Fluorescence Imaging using 3D PrimeSurface Ultra-Low Attachment Microplates
10 April 2018

Culturing cells in 3D provides a more a physiologically relevant approach to biomedical research, enabling the study of microenvironmental changes and interactions in health and disease. In this scientific poster, researchers from New Hampshire demonstrate the development of uniform, self-assemblied spheroids using S-BIO PrimeSurface ultra-low attachment cultureware. The PrimeSurface  96 and 384 ULA  plates are also suitable for subsequent brightfield and fluorescent imaging of spheroids, illustrated here with the Cytation 5 multi-mode reader.