ResourceLife Sciences
Brightfield and Fluorescence Imaging using 3D PrimeSurface Ultra-Low Attachment Microplates
9 Apr 2018Culturing cells in 3D provides a more a physiologically relevant approach to biomedical research, enabling the study of microenvironmental changes and interactions in health and disease. In this scientific poster, researchers from New Hampshire demonstrate the development of uniform, self-assemblied spheroids using S-BIO PrimeSurface ultra-low attachment cultureware. The PrimeSurface 96 and 384 ULA plates are also suitable for subsequent brightfield and fluorescent imaging of spheroids, illustrated here with the Cytation 5 multi-mode reader.
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PrimeSurface® 3D culture: Clear, Ultra-low Attachment Plates: 96 well, M bottom plates
PHC Corporation of North AmericaGrow Uniform Spheroids with Ultra-low Attachment PrimeSurface® Cell Culture Plate
PrimeSurface® 3D culture: Clear, Ultra-low Attachment Plates: 96 well, U bottom plates
PHC Corporation of North AmericaGrow Uniform Spheroids with Ultra-low Attachment PrimeSurface® Cell Culture Plate
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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.SpheroidsSpheroids are clusters of cells that have been grown in 3D culture to be used as <i>in vitro</i> model systems. These 3D microtissues can be used for toxicology testing, DMPK studies and many other applications involving cell analysis.