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Resolution of adeno-associated viral vector aggregates and fragments with Agilent Bio SEC-5

31 Jan 2022

Adeno-associated viruses (AAVs) are a promising new class of biotherapeutic with many proven applications. This application note demonstrates the chromatographic resolution of AAV aggregates and fragments using an Agilent Bio SEC-5 column.

Agilent Bio SEC-5

Agilent Technologies

Agilent Bio SEC-5 HPLC columns are packed with 5 µm silica particles coated with a proprietary, neutral, hydrophilic layer for maximum efficiency and stability. Our specially designed packing also promotes high pore volume, improving both peak capacity and resolution. 

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Resolution of adeno-associated viral vector aggregates and fragments with Agilent Bio SEC-5