ResourceDrug discovery > Lead Discovery
Increase throughput by recording in unattended mode on the SyncroPatch384
27 Nov 2020This application note demonstrates recordings of hNaV1.5 expressed in CHO cells on the SyncroPatch 384 in unattended mode. In a 6 hour period, 10 compound plates were prepared, 10 NPC-384 chips were recorded and success rates, IC50s and Z’ values were calculated using 7 different compounds in duplicate on each plate, along with positive and negative controls.
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SyncroPatch 384
Nanion Technologies GmbHThe SyncroPatch 384 is a revolutionary automated patch clamp system combining high quality electrophysiological data acquisition and analysis with state-of-the-art liquid handling. With 384 amplifier channels and a 384-pipetting head, up to 384 cells can be recorded in parallel, resulting in a throughput of up to 20,000 high-quality data points per day.