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Application Note: High-throughput analysis of 1,4-dioxane in drinking water using SPME Arrow–trap with multi-step enrichment (MSE)
13 September 2023

In this application note, Markes International presents a study in which solid-phase microextraction (SPME) Arrow–trap with multi-step enrichment (MSE®) on the Centri® extraction and enrichment platform was combined with gas chromatography–mass spectrometry (GC–MS) to analyze levels of the contaminant 1,4-dioxane in water samples. The system detected 1,4-dioxane at the lowest calibration point of 0.01 µg/L (10 ppt), which is beyond the detection limits required in German REACH and US EPA regulations.